Screening of new psychoactive substances in human plasma by magnetic solid phase extraction and LC-QTOF-MS

Analysis of 2,5-dimethoxy-amphetamines and 2,5-dimethoxy-phenethylamines aiming their determination in biological matrices: a review

“…In a very recent study, Hwang et al [ 155 ] have reported a new screening of 40 NPS in human plasma using a magnetic solid-phase extraction followed by liquid chromatography quadrupole time-of-flight mass spectrometry (LC–QTOF-MS). The extractive method is based on the use of a magnetic sorbent dispersed in the sample solution that can be separated by an external magnetic field due to the presence of magnetic nanoparticles.…”

Preparation of amphiphilic poly(divinylbenzene-co-N-vinylpyrrolidone)-functionalized polydopamine magnetic nanoadsorbents for enrichment of synthetic cannabinoids in wastewater

“…Key benefits of the MSPE process include low organic solvent use, quick separation, simplicity of use, and effortless recycling. 52 Fe 3 O 4 nanoparticles are frequently employed in MSPE due to their advantageous properties, such as easy surface modification and straightforward production processes. 53 Polydopamine (PDA) is a good example of a functionalized material that exhibits versatile coating capabilities and offers numerous opportunities for further chemical modifications through its functional groups, including amino and phenolic hydroxyl groups.…”

Isolation and quantification of synthetic cannabinoid receptor agonists in human urine using membrane-assisted solvent extraction followed by liquid chromatography-tandem mass spectrometry

“…In addition, new sorbents based on magnetic materials have allowed rapid and more efficient extractive procedures by dispersing the sorbent into the sample/extract by magnetic stirring. 13 Therefore, the use of sorbents such as COOH-functionalized multi-walled carbon nanotubes with magnetic nanoparticles (COOH-mMWCNTs) 14 and magnetite nanoparticles coated with poly ortho -aminophenol 15 has been proposed for SCRA enrichment from plasma, and the procedures can be considered examples of dispersive solid phase extraction (dSPE) with magnetic sorbents [magnetic solid phase extraction (m-SPE)]. Other strategies recently reported for SCRAs are those based on modified QuEChERS for pre-treating blood and urine 16 and solid phase microextraction (SPME).…”