Screening of plants of Amaryllidaceae and related families from Panama as sources of acetylcholinesterase inhibitors

Calderón, Ángela I.; Cubilla, Milagros; Espinosa, Alex; Gupta, Mahabir P.

doi:10.3109/13880200903418514

Cited by 17 publications

(8 citation statements)

References 15 publications

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“…43 Several species were found to contain the alkaloid galanthamine. 45 The extracts of Amaryllidaceae species belonging to the genera Hippeastrum and Rhodophiala have been screened for their anti-Trichomonas vaginalis potential, a flagellated protozoan that parasitizes the urogenital human tract and causes trichomonosis, the most prevalent non-viral sexually transmitted diseases (STD) worldwide. 44 The first comprehensive study on the AChE inhibitory activity in the species of family Amaryllidaceae and thirteen related families from Panama has also been reported recently.…”

Section: Occurrence Isolation and Identificationmentioning

confidence: 99%

“…44 The first comprehensive study on the AChE inhibitory activity in the species of family Amaryllidaceae and thirteen related families from Panama has also been reported recently. 45 The extracts of Amaryllidaceae species belonging to the genera Hippeastrum and Rhodophiala have been screened for their anti-Trichomonas vaginalis potential, a flagellated protozoan that parasitizes the urogenital human tract and causes trichomonosis, the most prevalent non-viral sexually transmitted diseases (STD) worldwide. 46 All the active fractions from R. bifida, H. breviflorum, H. vittatum, and H. psittacinum were found to contain lycorine and lycosinine as major components.…”

Section: Occurrence Isolation and Identificationmentioning

confidence: 99%

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Amaryllidaceae and Sceletium alkaloids

Jin

2011

Nat. Prod. Rep.

104

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Section: Occurrence Isolation and Identificationmentioning

confidence: 99%

Section: Occurrence Isolation and Identificationmentioning

confidence: 99%

Amaryllidaceae and Sceletium alkaloids

Jin

2011

Nat. Prod. Rep.

104

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“…Inflorescences are erect and located at the terminal branch. Its flowers are white with a red to purple line through the center; they bloom in the nighttime (Bos, 1984;Hyde et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

“…It has many ethnomedicinal usages, including boiling the roots in water and using to fight illness (Moshi et al, 2012), collecting rainwater from its leaves to treat ear pain, using the decoction of its bark to treat malnutrition (Lacroix et al, 2011), and squeezing or chewing its leaves and roots to induce labor (Kamatenesi-Mugisha and Oryem-Origa, 2007). It has also been reported to have antimalarial activity (Lacroix et al, 2011) and to be an acetylcholinesterase inhibitor (Calderon et al, 2010). In addition, D. fragrans can reduce on pollutants such as bisphenol a, formaldehyde, toluene and xylene (Wolverton 1997;Saiyood et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

The Diurnal and Nocturnal Floral Scent of Dracaena fragrans (L.) Ker Gawl. in Thailand

Julsrigival¹,

Julsrigival²,

Chansakaow³

2020

CMUJNS

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Dracaena fragrans (L.) Ker Gawl., with its green leaves and attractive shape, is a popular ornamental plant in Thailand, used for both interior decorating and outdoor landscaping. Its fragrant flowers only bloom at night. This study investigated the volatile chemicals from the flowers of D. fragrans during the day and night. Volatile compounds were extracted by Head Space Solid Phase Micro-extraction (HS-SPME) technique and determined by Gas Chromatography-Mass Spectrometry (GC-MS). Thirty compounds were identified; sesquiterpenes were the most prevalent (α-farnesene, 23.1-50.8%). The composition of the volatile compounds from the flowers differed between day and night.

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“…Panamanian plants have been evaluated for their biological activities on a diverse range of disease targets. They have been studied inter alia as cytotoxic to cancer cell lines, antimalarial, antileishmanial, antimicrobial, antiviral, larvicidal, antioxidant, immunosupressive, acetylcholinesterase inhibitors, and antihypertensive agents [6][7][8][9][10]. Research on the highly diverse Panamanian flora proposes new economical and medicinal ventures attractive to the pharmaceutical industry.…”

mentioning

confidence: 99%

A Quarter Century of Pharmacognostic Research on Panamanian Flora: A Review

Caballero‐George¹,

Gupta²

2011

Planta Med

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Introduction !Medicinal plants remain an endless source of new drugs, new drug leads, and new chemical entities (NCEs) [1]. In developing countries, medicinal plants have been the most accessible source of medicaments and in rural areas, traditional medicine is part of the first line of treatment for common pathologies [2]. The geographical characteristics of the Isthmus of Panama are responsible for its highly diverse flora and fauna. This diversity promotes the use of plants in traditional medicine by the Amerindian groups and the rural population, which have limited access to modern drugs. Panama is a unique terrestrial bridge of great biological importance. Panamanian flora is one of the richest in the world with an estimate of 9893 different species of vascular plants, of which 1327 (13.4 %) are endemic [3]. There is a large number of nonvascular species but they have not been investigated fully. Panama has over 687 species of ferns and about 1000 species of orchids, of which 50 % are endemic. Epiphytes, lianas, and climbers are a major component of the Panamanian tropical forest. Mosses abound in moist cloud forests as well as other parts of the country. Panama is considered one of the botanical "hot spot" countries and occupies the fourth place in the world in number of vascular species [4]. The number of species per 10 000 km 2 ranks even much higher than in bigger countries like India, China, and the United States [5]. Evidence of the biomedical potential of herbal drugs used in Panamanian traditional medicine is continually being reported. Panamanian plants have been evaluated for their biological activities on a diverse range of disease targets. They have been studied inter alia as cytotoxic to cancer cell lines, antimalarial, antileishmanial, antimicrobial, antiviral, larvicidal, antioxidant, immunosupressive, acetylcholinesterase inhibitors, and antihypertensive agents [6][7][8][9][10]. Research on the highly diverse Panamanian flora proposes new economical and medicinal ventures attractive to the pharmaceutical industry. In the National Science Strategic Plan 2010-2014, a very high priority has been assigned to the study and utilization of Panamanian biodiversity as a source Supporting information available at

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Screening of plants of Amaryllidaceae and related families from Panama as sources of acetylcholinesterase inhibitors

Cited by 17 publications

References 15 publications

Amaryllidaceae and Sceletium alkaloids

Amaryllidaceae and Sceletium alkaloids

The Diurnal and Nocturnal Floral Scent of Dracaena fragrans (L.) Ker Gawl. in Thailand

A Quarter Century of Pharmacognostic Research on Panamanian Flora: A Review

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