Screening of Secondary Metabolites and Antibacterial Activity of Acacia concinna

Todkar, Sachin S.; Chavan, Vinodkumar; Kulkarni, A. S.

doi:10.3923/jm.2010.974.979

Cited by 20 publications

(20 citation statements)

References 2 publications

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“…Small quantity of freshly prepared n-hexane, chloroform, methanol and aqueous extracts of R. dumetorum were subjected to preliminary quantitative phytochemical investigation for detection of phytochemicals such as alkaloids, flavonoids, reducing sugars, saponins, phenolic compounds, proteins and amino acids, tannins, gums and mucilage using the standard methods (Mujeeb et al, 2014;Todkar et al, 2010;Thamaraiselvi et al, 2012;Auwal et al, 2014;Mandal et al, 2013;Chinedu et al, 2015;Sumbul et al, 2012).…”

Section: Phytochemical Screeningmentioning

confidence: 99%

Antioxidant potential and cytotoxicity of Randia dumetorum Lam. leaf extract

Abdullah-Al-Ragib¹,

Hossain²,

Hossain³

et al. 2017

J. Pharmacognosy Phytother.

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The aim of the current study was to explore the antioxidant potential and cytotoxicity of different 'fractions from the leaf extract of Randia dumetorum. Proximate analysis and phytochemical screening were done with standard protocol. The antioxidant activity was evaluated by using reducing power assay, total antioxidant capacity determination, determination of total phenolic content, determination of total flavonoid content and reduction of ferric ions by ortho-phenanthroline color method. In the antioxidant studies, ascorbic acid, gallic acid and butylated hydroxy toluene (BHT) were used as standard antioxidant compound. The brine shrimp lethality test was used to examine cytotoxicity. In the proximate analysis, moisture content, total ash value, acid insoluble ash and water-soluble ash value were found in the leaf of R. dumetorum. Concerning the phytochemical screening, there was the presence of glycosides, flavonoids, reducing sugars, saponins, phenolic compounds, tannins on different fractions, but the absence of gums and mucilage, alkaloid, protein, and amino acid. The results show that all the extracts of R. dumetorum leaf possess significant antioxidant activity. 'The methanol and water extracts of the leaves showed significant cytotoxic activity as compared to dimethyl sulfoxide (DMSO) (LC 50 1.07 µg/ml). These findings suggest that R. dumetorum leaves might be a good antioxidants source and possess mild cytotoxic effect.

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Section: Phytochemical Screeningmentioning

confidence: 99%

Antioxidant potential and cytotoxicity of Randia dumetorum Lam. leaf extract

Abdullah-Al-Ragib¹,

Hossain²,

Hossain³

et al. 2017

J. Pharmacognosy Phytother.

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“…The leaves, bark and pods have been used as a herbal medicine for emetic, purgative and expectorant treatments (Gafur et al, 1997;Kukhetpitakwong et al, 2006;Raja and Sivaraj, 2012). In addition, antioxidant, anti-coagulant, anti-platelet, anti-thrombotic, antidermatophytic and immune adjuvant activities are some of the valuable pharmacological properties of the plant (Kapoor et al, 1969, Kukhetpitakwong et al, 2006Todkar et al, 2010;Rao et al, 2014;Sharma et al, 2014). Nonetheless, no study has been conducted regarding the allelopathic properties of this plant species.…”

Section: Introductionmentioning

confidence: 99%

Allelopathic activity of Acacia concinna pod extracts

Boonmee

Kato‐Noguchi

2017

Emir. J. Food Agric

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“…Chemical pesticides, which are used against both agricultural pests and medically/veterinarily important insect species, are highly toxic to humans and the environment. Plant secondary metabolites play an important role in plant defence systems against pathogens and pests by antibacterial, antiviral and antifungal action . They also have a broad spectrum of insecticidal activity .…”

Section: Introductionmentioning

confidence: 99%

“…Plant secondary metabolites play an important role in plant defence systems against pathogens and pests by antibacterial, antiviral and antifungal action. 1,2 They also have a broad spectrum of insecticidal activity. 3,4 Many of them are characterised by repellent or antifeedant activity.…”

Section: Introductionmentioning

confidence: 99%

Structure-related antifeedant activity of halolactones with a p -menthane system against the lesser mealworm, Alphitobius diaperinus Panzer

et al. 2013

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Chemical transformation of the piperitone molecule by the introduction of a lactone function and a halogen atom strongly changed its antifeedant properties against the lesser mealworm. Optimum activity is dependent on the presence of a chlorine atom at C-5 of the cyclohexane ring. The activity of bromo- and iodolactones depended strongly on the chiral centre configuration and the halogen substituent.

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Screening of Secondary Metabolites and Antibacterial Activity of Acacia concinna

Cited by 20 publications

References 2 publications

Antioxidant potential and cytotoxicity of Randia dumetorum Lam. leaf extract

Antioxidant potential and cytotoxicity of Randia dumetorum Lam. leaf extract

Allelopathic activity of Acacia concinna pod extracts

Structure-related antifeedant activity of halolactones with a p -menthane system against the lesser mealworm, Alphitobius diaperinus Panzer

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