Screening, rubella vaccination, and childhood hearing impairment in Taiwan

Lai, Der Chung; Tseng, Yen-Cheng; Lin, Chii Jeng; Guo, How‐Ran

doi:10.1016/j.ridd.2014.07.051

Cited by 6 publications

(4 citation statements)

References 40 publications

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“…Similar decreasing trends with age were also observed in a study on a representative sample of the Dutch population (Spee-van der Wekke, den Ouden, Meulmeester, & Radder, 2000) and the Second National Sample Survey on Disability of China (Zheng et al, 2008). However, using the same registry, we found that some other developmental disabilities, including intellectual disabilities (Lai et al, 2012b) and hearing impairment (Lai et al, 2014), increased with age in childhood. We believe the main reasons are that most cases of those developmental disabilities are rarely fatal and that a large proportion of cases are not curable.…”

Section: Tablementioning

confidence: 81%

Gender and geographic differences in the prevalence of reportable childhood speech and language disability in Taiwan

Tseng

Lai

Guo

2015

Research in Developmental Disabilities

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Section: Tablementioning

confidence: 81%

Gender and geographic differences in the prevalence of reportable childhood speech and language disability in Taiwan

Tseng

Lai

Guo

2015

Research in Developmental Disabilities

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“…We also found that conditions which are more likely to be diagnosed objectively (with more objective signs and quantitative outcomes) tended to have lower male-to-female RRs. For example, during our study period, HI was diagnosed on the basis of on pure tone hearing test results, which are quantitative outcomes with decibel as the unit, 19 and ASD was diagnosed on the basis of the DSM-IV diagnostic criteria 8,16 ( [1] qualitative impairment in social interaction, [2] qualitative impairments in communication, and [3] restricted repetitive and stereotyped patterns of behavior interests, and activities), which are mainly qualitative outcomes. Speci cally, HI (1.08), LFMO (1.12), VI (1.28), and MD (1.34) are more likely to be diagnosed objectively and had the lowest male-tofemale RRs, followed by ID (1.37), while SLD (1.57) and ASD (5.88) relied more on subjective symptoms (qualitative outcomes) for diagnosis and had the highest male-to-female RRs.…”

Section: Discussionmentioning

confidence: 99%

“…15 The registry have become a valuable source of information for research. [16][17][18][19][20][21][22] When a child is suspected to have a disability that is quali ed for the bene ts, a parent or guardian can apply for certi cation through the local government o ce in the residential area on the child's behalf. To be certi ed, a patient must t the criteria listed by the government (Supplement Table I) 23 and be con rmed by a doctor accredited by the government.…”

Section: The Disability Registry System In Taiwanmentioning

confidence: 99%

Male as the Disadvantaged Sex for Childhood Disabilities: Analysis of Data From the National Disability Registry of Taiwan

Lai

Guo

Tseng

2021

Preprint

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Background: Many studies have examined sex differences in specific types of childhood disability, but data on the full range of disability are limited. Such data allow comparisons among disabilities and are valuable to the inference of etiology. To provide benefits and services, the Taiwanese government certifies disabled citizens and maintains a registry. We used the registry to evaluate sex differences in childhood disability and assess changes over time.Methods: We analyses the registry data from 2000 to 2011 and included all children who were at least 3 years of age, because certification before 3 years of age was discouraged by the government. We calculated the male-to-female rate ratios (RRs) for all disabilities combined and nine major disability categories, namely autism spectrum disorders (ASD), hearing impairment (HI), intellectual disability (ID), loss of function of major organs (LFMO), motor disability (MD), multiple disabilities, speech and language disability (SLD), visual impairment (VI), and other disabilities. In addition, we assessed the changes in the RRs over time.Results: The total number of cases between 3 to 17 years of age registered each year ranged between 49242 and 61717. Males generally had higher prevalence than females, and disabilities due to primarily neurodevelopmental conditions (ASD, ID, and SLD) had higher male-to-female RRs than disabilities due to primarily physical conditions (HI, LFMO, MD, and VI). The RRs of all disabilities combined increased over time, but the sex differences in ID, MD, and “other disabilities” decreased over time, while those in ASD, SLD, and multiple disabilities increased. The RRs of all disabilities combined decreased with age in most years, but the trends were different across individual disabilities.Conclusions: Male is the disadvantaged sex for childhood disabilities. The sex differences in disabilities due to primarily neurodevelopmental conditions were more prominent than those in disabilities due to primarily physical conditions. With the decreasing number of children given birth and growing awareness of sexual disparity during the study period in Taiwan, the RRs had an increasing time trend, instead of decreasing, which suggested that genetic causes have larger contributions to the sex differences in childhood disability than environmental causes.

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“…Recent advances in molecular genetics have revolutionized the assessment armamentarium of pediatric SNHL, enabling us to ascertain the etiology in 40-60% of the children with SNHL [13,14]. However, the clinical significance and contribution of the environmental factors that might lead to pediatric SNHL in these children largely remains unclear [8,11,12,15,16].…”

Section: Introductionmentioning

confidence: 99%

The prevalence and demographic features of congenital cytomegalovirus infection in an urban area of East Asia: A population-based study

et al. 2021

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Congenital cytomegalovirus (cCMV) infection is the leading environmental cause of childhood hearing impairment. However, its significance remains largely undocumented in many regions of the world. The purpose of this study was to investigate the prevalence and clinical features of cCMV infection in East Asia. Neonates born at a municipal hospital in Taipei were prospectively recruited and underwent concurrent hearing and CMV screenings. Those who failed the hearing screening or screened positive for CMV were subjected to a focused audiological and/or virological surveillance. The characteristics of the newborns and their mothers were compared between the CMV-positive and CMV-negative groups. Of the 1,532 newborns who underwent concurrent hearing and CMV screenings, seven (0.46%) were positive for cCMV infection. All seven CMV-positive newborns were asymptomatic at birth, and none of them developed hearing or other symptoms during a follow-up period of 14.4±6.3 months. The mothers of the CMV-positive newborns demonstrated higher gravidity (2.4 ± 1.4 vs. 2.1 ± 1.2) and parity (2.0 ± 1.2 vs. 1.6 ± 0.7) than those in the CMV-negative group; however, the difference did not reach statistical significance. The prevalence of cCMV infection in Taipei newborns was 0.46%, which is slightly lower than that of other populations and that of a previous report in the Taiwanese population. The relatively low prevalence in this study might be attributed to the improved public health system and decreased fertility rate in Taiwan.

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Screening, rubella vaccination, and childhood hearing impairment in Taiwan

Cited by 6 publications

References 40 publications

Gender and geographic differences in the prevalence of reportable childhood speech and language disability in Taiwan

Gender and geographic differences in the prevalence of reportable childhood speech and language disability in Taiwan

Male as the Disadvantaged Sex for Childhood Disabilities: Analysis of Data From the National Disability Registry of Taiwan

The prevalence and demographic features of congenital cytomegalovirus infection in an urban area of East Asia: A population-based study

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