Screening strategies for non-alcoholic fatty liver disease: a holistic approach is needed

Kasper, Philipp; Demir, Münevver; Steffen, Hans‐Michael

doi:10.3350/cmh.2023.0059

Cited by 2 publications

(2 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Using the FLI, the study found that the prevalence of fatty liver disease (FLI ≥ 60) in Korean adults aged 20 years and older increased from 13.3% in 2009 to 15.5% in 2017. This increase was particularly prominent among men and the younger age group (20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35)(36)(37)(38)(39). Furthermore, the study found that people with T2DM had the highest prevalence of fatty liver disease, with a steep increase seen in the young T2DM population.…”

Section: Description Of Studies That Appreciated the Diagnostic Role ...mentioning

confidence: 90%

See 1 more Smart Citation

The Role of the Fatty Liver Index (FLI) in the Management of Non-Alcoholic Fatty Liver Disease: A Systematic Review

Biciusca,

Stan,

Balteanu

et al. 2023

Diagnostics

View full text Add to dashboard Cite

Currently, non-alcoholic fatty liver disease is the most common liver disease worldwide, with a prevalence of 32%. It is much more common among men (40%) and among patients with metabolic comorbidities such as obesity, diabetes and dyslipidemia. Being an asymptomatic disease, the diagnosis is often established on the basis of imaging methods, with an important role given to abdominal ultrasonography, computed tomography and magnetic resonance imaging. In order to facilitate diagnosis, experts have introduced a series of blood biomarkers. Two biomarker panels are currently validated for the diagnosis of non-alcoholic fatty liver disease: the fatty liver index, and the hepatic steatosis index. The fatty liver index has been in use in medical practice for over 17 years and has demonstrated its accuracy in various studies that compared it with other diagnostic methods, highlighted its role in screening patients with cardiovascular risk and validated the effects of different diets and drugs that are proposed for the treatment of the disease. In the management of non-alcoholic fatty liver disease, the fatty liver index is an important algorithm in the diagnosis and prognosis of patients with metabolic risk. Taking into account the diversity of drugs to be approved in the treatment of non-alcoholic fatty liver disease, the fatty liver index will become an effective tool in monitoring the effects of these therapies.

show abstract

Section: Description Of Studies That Appreciated the Diagnostic Role ...mentioning

confidence: 90%

“…Considering the global burden of NAFLD, there is a real need to improve awareness of the health risks of NAFLD. Thus, it is important to implement screening methods that include an assessment of multiple organs beyond liver damage [35].…”

Section: Introductionmentioning

confidence: 99%