Screening Success in the Age of Autism

Additive interaction between birth asphyxia and febrile seizures on autism spectrum disorder: a population-based study

“…It includes a detailed survey of the child’s general health history during the fetal and perinatal periods, previous medical conditions, and a thorough assessment of family background. Key factors such as the child’s age [ 32 ], sex [ 33 ], district [ 34 ], Body Mass Index (BMI) [ 35 ], birth weight [ 36 ], gestational age [ 37 ], mode of delivery [ 38 ], feeding practices [ 39 ], parental age [ 40 , 41 ], educational levels of the parents [ 42 ], parents’ personalities [ 43 ], maternal psychological status [ 44 ], complications during pregnancy [ 45 ] and the annual household income [ 34 ] are all considered. The questionnaire is comprehensive, comprising 44 items in total, each designed to capture essential data points crucial for understanding the multifaceted influences on a child’s development.…”

“…Additionally, we established three models to better isolate the association between BA/FS and ASD as well as reduce potential bias:1) unadjusted (Model 1); 2) adjusted for demographic features (Model 2); 3) adjusted for demographics plus BA, FS, or ASD-related covariates (Model 3). The selection of covariates was based on factors extensively reported in the literature as having significant associations with either the independent variables (BA, FS) or the dependent variable (ASD) [ 32 – 45 ]. These factors may potentially alter the relationship between the independent and dependent variables within the model.…”