Screening women at high risk of breast cancer on the basis of evidence

Warren, Ruth

doi:10.1016/s0720-048x(00)00237-0

Cited by 17 publications

(11 citation statements)

References 120 publications

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“…• to start mammography screening at an earlier age, that has been proved to be effective in single trials [28]; • to undergo palpation and ultrasounds if they were found to have a dense parenchymal pattern which is associated with high grade cancers, that is both a risk factor and a reason for impaired screening sensitivity [29]; • to follow a more intensive surveillance protocol if they are at high risk for hereditary cancer, although carcinogenic risks associated with radiation in these women and the benefit of early detection are not fully known [30]; • to undergo mammography examination every year if they are under hormone replacement therapy (HRT), as a reduction in the sensitivity of screening mammography of between 7 and 21% in current HRT users has been observed [31] and the preclinical phase of cancers arising in these women, under estrogenic stimulation, may be shorter.…”

Section: Breast Cancermentioning

confidence: 99%

Early detection of cancer: Ideas for a debate

Gennari

Veronesi

Andreoli

et al. 2007

Critical Reviews in Oncology/Hematology

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Section: Breast Cancermentioning

confidence: 99%

Early detection of cancer: Ideas for a debate

Gennari

Veronesi

Andreoli

et al. 2007

Critical Reviews in Oncology/Hematology

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“…Solid lumps require further examination in order to determine the presence of cancer. According to Warren (2001), breast ultrasound is low cost and radiation free and can be useful if combined with family history, but it is not recommended as a stand alone technique for breast cancer detection. This is due to its low sensitivity for ductal microcalcifications in the breast.…”

Section: Ultrasoundmentioning

confidence: 99%

Thermal Detection of Embedded Tumors Using Infrared Imaging

Mital

Scott

2006

Journal of Biomechanical Engineering

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Breast cancer is the most common cancer among women. Thermography, also known as thermal or infrared imaging, is a procedure to determine if an abnormality is present in the breast tissue temperature distribution. This abnormality in temperature distribution might indicate the presence of an embedded tumor. Although thermography is currently used to indicate the presence of an abnormality, there are no standard procedures to interpret these and determine the location of an embedded tumor. This research is a first step towards this direction. It explores the relationship between the characteristics (location and power) of an embedded heat source and the resulting temperature distribution on the surface. Experiments were conducted using a resistance heater that was embedded in agar in order to simulate the heat produced by a tumor in the biological tissue. The resulting temperature distribution on the surface was imaged using an infrared camera. In order to estimate the location and heat generation rate of the source from these temperature distributions, a genetic algorithm was used as the estimation method. The genetic algorithm utilizes a finite difference scheme for the direct solution of the Pennes bioheat equation. It was determined that a genetic algorithm based approach is well suited for the estimation problem since both the depth and the heat generation rate of the heat source were accurately predicted.

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“…This is compounded by the use of hormone replacement therapy (HRT) which increases density [20]. It is also important when young women at elevated risk are screened, since the various causes of elevated risk are associated with dense patterns [21].…”

Section: Mammographic Density and Breast Cancer Riskmentioning

confidence: 99%

Update on the importance of parenchymal patterns and breast cancer risk

Ding

Warren

2004

Breast Cancer Online

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Mammographic density is a well-documented independent risk factor for breast cancer. Measurements of density come in various forms, ranging from qualitative descriptions to quantitative assessments or a combination of both. The different means of examining density lead to variations in density-risk relationship. Currently there is no consensus on which method is preferable. The interrelation of mammographic density with other risk factors is crucial to density-risk assessments, since each of these risk factors can influence density on its own. Mammographic density can be modified through hormonal and chemical means, which can have important implications on mammographic sensitivity, accuracy in cancer diagnosis and cancer prevention.

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Screening women at high risk of breast cancer on the basis of evidence

Cited by 17 publications

References 120 publications

Early detection of cancer: Ideas for a debate

Early detection of cancer: Ideas for a debate

Thermal Detection of Embedded Tumors Using Infrared Imaging

Update on the importance of parenchymal patterns and breast cancer risk

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