BackgroundHip fractures are a major healthcare problem, presenting a challenge and burden to individuals and healthcare systems. The number of hip fractures globally is rising. The majority of extracapsular hip fractures are treated surgically.
ObjectivesTo assess the relative e ects (benefits and harms) of all surgical treatments used in the management of extracapsular hip fractures in older adults, using a network meta-analysis of randomised trials, and to generate a hierarchy of interventions according to their outcomes.
Search methodsWe searched CENTRAL, MEDLINE, Embase, Web of Science and five other databases in July 2020.
Selection criteriaWe included randomised controlled trials (RCTs) and quasi-RCTs comparing di erent treatments for fragility extracapsular hip fractures in older adults. We included internal and external fixation, arthroplasties and non-operative treatment. We excluded studies of hip fractures with specific pathologies other than osteoporosis or resulting from high-energy trauma.
Data collection and analysisTwo review authors independently assessed studies for inclusion. One review author completed data extraction which was checked by a second review author. We collected data for three outcomes at di erent time points: mortality and health-related quality of life (HRQoL)both reported within 4 months, at 12 months and a er 24 months of surgery, and unplanned return to theatre (at end of study follow-up).We performed a network meta-analysis (NMA) with Stata so ware, using frequentist methods, and calculated the di erences between treatments using risk ratios (RRs) and standardised mean di erences (SMDs) and their corresponding 95% confidence intervals (CIs). We also performed direct comparisons using the same codes.
Surgical interventions for treating extracapsular hip fractures in older adults: a network meta-analysis (Review)