Scrotal Hyperthermia, Hormonal Disturbances, Testicular Hypoperfusion, and Backflow of Toxic Metabolites in Varicocele

Majzoub, Ahmad; Cho, Chak‐Lam; Agarwal, Ashok; Esteves, Sandro C.

doi:10.1007/978-3-319-79102-9_3

Cited by 2 publications

(1 citation statement)

References 48 publications

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“…In certain cases varicocele can even impair the development of testicles. Varicocele can lead to the increased state of the temperature of testes and thereby causes the Understanding Male Infertility for Promising ART DOI: http://dx.doi.org/10.5772/intechopen.98504 reflux of metabolites (toxic) of adrenal vein to the left kidney [9]. It is reported that 40 percent of infertile men have varicocele being diagnosed as the primary reason of the ailment.…”

Section: Varicocelementioning

confidence: 99%

Understanding Male Infertility for Promising ART

Zargar¹,

A²,

Lateef³

et al. 2021

Infertility and Assisted Reproduction

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Infertility is a serious problem of not being able to conceive despite regular intercourse for more than a year. Natural conception is seen to be achieved in 80%–85% of couples. About 15% of couples suffer infertility with male factor contributing to almost 50% of cases. Paradoxically, on traditional assessment, the underlying etiology of male contribution towards infertility remains unrecognized in 30% of the patients and thereby grouped as idiopathic. Diagnostics of male infertility cannot therefore be limited to usual semen analysis only. The spectrum of the recent research encourages the experts in the field to approach the Clinical, Molecular and cytogenetic shades associated with the problem besides secondary factors like life style and environment. Clinical assessment sums the medical history and physical examination of the affected individual. Molecular and cytogenetic analysis help gain new insights in understanding the problem and thereby an advantage for a successful assisted reproductive treatment (ART). Given the cost and burden ART puts in and prior to application of any invasive techniques, understanding precisely the etiology associated with male infertility is essential for the fertility specialist to circumvent inefficient or any unproductive steps in the fertilization process besides helping in counseling patients on their chance of success with the use of reproductive technology.

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Section: Varicocelementioning

confidence: 99%

Understanding Male Infertility for Promising ART

Zargar¹,

A²,

Lateef³

et al. 2021

Infertility and Assisted Reproduction

View full text Add to dashboard Cite

show abstract

Standardized Laboratory Procedures, Quality Control and Quality Assurance Are Key Requirements for Accurate Semen Analysis in the Evaluation of Infertile Male

Agarwal

Sharma

Gupta

et al. 2022

World J Mens Health

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Semen analysis is a basic test for evaluating male fertility potential, as it plays an essential role in driving the future management and treatment of infertility in couples. Manual semen analysis includes the evaluation of both macroscopic and microscopic parameters, whereas automated semen analysis is conducted through a computer-aided sperm analysis system and can include additional parameters that are not evaluated by manual analysis. Both quality control (QC) and quality assurance (QA) are important to ensure reproducible results for semen analysis, and represent fundamental checks and balances of all stages (pre-analytical, analytical, and post-analytical) of semen analysis. To ensure accuracy and precision, the laboratory technicians' performance should be evaluated biannually. This narrative review aims to describe standardized laboratory procedures for an accurate assessment of semen parameters that incorporate both QC and QA practices.

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Scrotal Hyperthermia, Hormonal Disturbances, Testicular Hypoperfusion, and Backflow of Toxic Metabolites in Varicocele

Cited by 2 publications

References 48 publications

Understanding Male Infertility for Promising ART

Understanding Male Infertility for Promising ART

Standardized Laboratory Procedures, Quality Control and Quality Assurance Are Key Requirements for Accurate Semen Analysis in the Evaluation of Infertile Male

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