Scrotal Ultrasonic Features of Congenital Bilateral Absence of Vas Deferens

Li, Jun; Zhi-qian, Wang; Zhou, Mingyang; Li, Min; Zhan, Weiwei

doi:10.1097/ruq.0000000000000278

Cited by 6 publications

(7 citation statements)

References 7 publications

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“…Therefore, the diagnosis of agenesis is based on nonvisualization of this segment. 12,18 As mentioned earlier, this depends on a combination of grayscale and Doppler imaging with and without graded compression (Figs. 15,16,17) Like the vas deferens, the epididymis arises from the Wolffian duct and may be atretic itself or altered due to obstruction.…”

Section: Congenital Absencementioning

confidence: 95%

“…In a previous study, Middleton et al 7 showed that the straight, suprascrotal segment of the vas can be seen 100% of the time. Therefore, the diagnosis of agenesis is based on nonvisualization of this segment 12,18 . As mentioned earlier, this depends on a combination of grayscale and Doppler imaging with and without graded compression (Figs.…”

Section: Common Abnormalities Of the Vas Deferensmentioning

confidence: 99%

“…Like the vas deferens, the epididymis arises from the Wolffian duct and may be atretic itself or altered due to obstruction. In almost all cases, there are associated changes in the epididymis, ranging from complete or partial atresia, various degrees of cystic changes, heterogeneity, and nodularity 18 . In a study of 85 men with CBAVD, abnormalities in the epididymis were universal 12 .…”

Section: Common Abnormalities Of the Vas Deferensmentioning

confidence: 99%

“…Obstructive azoospermia does not affect testicular volume but almost always produces alterations in the vas deferens and epididymides. 18,19 When dilation of the vas deferens is seen on a scrotal examination, the examination should be extended superiorly into the suprascrotal and prepubic regions to identify the level and cause of the obstruction (Fig. 14 A and video 14B, http://links.lww.…”

Section: Common Abnormalities Of the Vas Deferens Obstructionmentioning

confidence: 99%

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Ultrasound of the Normal and Abnormal Vas Deferens

Kerr

Middleton²

2022

Ultrasound Quarterly

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The extrapelvic portion of the vas deferens is readily visible with ultrasound but often overlooked. Several publications have described the scanning technique and the normal anatomy of the vas deferens. Sonographic evaluation of the vas deferens provides critical information in the workup of male infertility. Obstruction, inflammatory conditions, and neoplasms of the vas deferens can also be diagnosed with ultrasound. Knowledge of the normal and abnormal appearance of the vas deferens improves scans of the scrotum and expands the conditions that can be recognized and accurately diagnosed with ultrasound.

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Section: Congenital Absencementioning

confidence: 95%

Section: Common Abnormalities Of the Vas Deferensmentioning

confidence: 99%

Section: Common Abnormalities Of the Vas Deferensmentioning

confidence: 99%

Section: Common Abnormalities Of the Vas Deferens Obstructionmentioning

confidence: 99%

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Ultrasound of the Normal and Abnormal Vas Deferens

Kerr

Middleton²

2022

Ultrasound Quarterly

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“…B-ultrasound is the simplest and most harmless imaging examination method. It can not only clearly show the vas deferens through the transabdominal, scrotal, and transrectal methods (Schlegel et al, 1996;Daudin et al, 2000;Liu et al, 2017) but also detect whether the seminal vesicles, kidneys and other structures are abnormal (Lotti and Maggi, 2015). This method is always used by andrologists clinically during the diagnosis of CBAVD.…”

Section: Imaging Examinationmentioning

confidence: 99%

Congenital Bilateral Absence of the Vas Deferens

Cai

2022

Front. Genet.

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Congenital bilateral absence of the vas deferens (CBAVD) is clinically characterized by the absence of the bilateral vas deferens; the main clinical manifestation is infertility, accounting for 1–2% of male infertility cases. CBAVD may be accompanied by congenital abnormalities in the urogenital system and cystic fibrosis (CF)-related clinical manifestations. CBAVD can develop as a mild manifestation of CF or can be isolated. The main pathogenic mechanism of CBAVD is gene mutation, and CBAVD and CF have a common genetic mutation background. CFTR mutation is the main pathogenic cause of CBAVD and CF, and ADGRG2 mutation is the second most common cause. Although lack of the vas deferens in CBAVD patients causes infertility due to the inability to release sperm, the testes of CBAVD patients have spermatogenic function. Therefore, CBAVD patients can achieve fertility through sperm retrieval surgery and assisted reproductive technology (ART). However, gene mutations in CBAVD patients can have an impact on the ART outcome, and there is a risk of passing on gene mutations to offspring. For CBAVD patients and their spouses, performing genetic counseling (which currently refers mainly to CFTR mutation screening) helps to reduce the risks of genetic mutations being passed on to offspring and of offspring having CF with concomitant CBAVD.

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