This paper presents the effects of various properties on nanofluid flows and heat transfer over a permeable stretching sheet of variable thickness in the presence of a transverse magnetic field. Mathematically, the leading coupled partial differential equations are transformed into a self-similar system of ordinary differential equations through similarity variables, which are solved thereafter using Keller-box and Haar’s wavelet methods. Moreover, the impacts of various flow parameters involved in the physical problem are discussed thoroughly via tables and graphs. As findings, the analysis discloses that the nanofluid flow is significantly influenced by the physical parameters. Dynamically, the nanofluid flow is accelerated prominently with the strengthening in the injection process and decelerated in other situations. Furthermore, the obtained results are compared successfully with the earlier published findings.