Sea Bass Essence from Lates calcarifer Improves Exercise Performance and Anti-Fatigue in Mice

Abstract

Sea bass (Lates calcarifer) is rich in protein, amino acids, and long-chain omega 3 (omega-3), which have many health benefits. In East Asian food culture, soup is often eaten as a nutritional supplement. The purpose of this study was to investigate the benefits of Hi-Q sea bass essence (SBE) supplementation for improved exercise performance and anti-fatigue. Fifty male Institute of Cancer Research (ICR) mice were divided to five groups (10 mice/group) and administered different doses of SBE (EC): (1) vehicle (water); (2) isocaloric (0.94 g casein/kg/mice/day); (3) SBE-1X (1.04 g/kg/mice/day); (4) SBE-2X (2.08 g/kg/mice/day); and (5) SBE-4X (4.16 g/kg/mice/day). We found that SBE supplementation significantly improved more than 1.96-fold endurance exercise performance (p < 0.05) and more than 1.13-fold glycogen storage in the liver and muscles (p < 0.05), and had dose-dependent by SBE dose (p < 0.05). In addition, supplementation with SBE at different doses had significant effects on the fatigue-related biochemical markers, i.e., lactate, ammonia, and blood urea nitrogen (BUN) levels were reduced significantly (p < 0.05), and were also dose-dependent. In conclusion, supplementation with SBE for 4 weeks was able to effectively improve exercise performance and had an anti-fatigue effect. In addition, it did not cause any physiological or histopathological damage.

The anti-fatigue and sleep-aiding effects vary significantly among different recipes containing Ganoderma lucidum extracts

“…On the other hand, high-dosage GBS treatment solely reduced MDA levels in the livers by 22.1%, without significant changes in other indicators. Comparing these findings with recently reported literature, we observe that the reduction rates of serum lactate and serum urea nitrogen in our study fall within safe ranges, below 34.5% and 25.2%, respectively [ [93] , [94] , [95] ]. Similarly, the increases in hepatic glycogen and muscle glycogen were within acceptable limits, below 51.0% and within 45.0%, respectively [ 93 , 94 , 96 ].…”

“…Comparing these findings with recently reported literature, we observe that the reduction rates of serum lactate and serum urea nitrogen in our study fall within safe ranges, below 34.5% and 25.2%, respectively [ [93] , [94] , [95] ]. Similarly, the increases in hepatic glycogen and muscle glycogen were within acceptable limits, below 51.0% and within 45.0%, respectively [ 93 , 94 , 96 ]. Furthermore, the reduction rates of MDA levels in the livers and muscles in our study were also within safe ranges, below 52.8% and 54.7%, respectively [ 55 , 97 , 98 ].…”

DMC (2′,4′‐dihydroxy‐6′‐methoxy‐3′,5′‐dimethylchalcone) enhances exercise tolerance via the AMPK‐SIRT1‐PGC‐1α pathway in mice fed a high‐fat diet

“…And excessive fatigue can cause disorders of immunity and internal environment, and even cause organic diseases (Finsterer & Mahjoub, 2014). Energy depletion, metabolite accumulation, oxidative stress, and associated inflammation are the major causes of exercise‐induced fatigue, according to relevant studies (Osman & Mohamed, 2018; Tai et al, 2022; Wafi et al, 1985). At present, some substances (such as anabolic agents, β2‐receptor agonists, stimulants, glucocorticoids, and β‐receptor blockers) are commonly used to enhance exercise tolerance and reduce fatigue in a short time (Heuberger & Cohen, 2019).…”