Sealing Ability of Biodentine and Simvastatin for Repair of Furcation Perforation Using Dye Extraction Method

Abstract

Aim: This study aimed to evaluate the sealing ability of Biodentine and Simvastatin for the repair of furcal perforation using dye extraction method. Materials and Methods: Thirty extracted permanent human mandibular first molars were selected. Access cavities were prepared in all first molars while perforations were made at the furcation areas of only twenty five molars. Grouping of samples was done as follows, Group 1 (n = 10) in which perforations were repaired with Biodentine™, Group 2 (n = 10) in which perforations were repaired with Simvastatin, Group 3 (n = 5) in which perforations were left unrepaired (positive control) and Group 4 (n = 5) in which no perforations were done (negative control). The sealing ability in four groups was evaluated using dye extraction method. Statistical analysis was done using One-Way ANOVA test to compare the mean values of the different groups then pairwise comparisons were performed using Tukey's posthoc test. Results: The highest dye absorbance was recorded for the positive control group (0.081 ± 0.013) while the lowest value was recorded for the negative control group (0.003 ± 0.002). The mean value of Biodentine group (0.025 ± 0.009) was significantly lower than Simvastatin (0.069 ± 0.011). Conclusion: Sealing ability of Biodentine is significantly better than Simvastatin in furcal perforation repair.

Efficacy of Combination of Biodentine and Simvastatin as Pulp Capping Materials in Vital Pulpotomy of Primary Molars: Randomized Clinical Trial

“…Simvastatin group: Simvastatin powder (Al Debeiky Pharmaceutical, Cairo, Egypt) 1.5 mg was mixed with 3 drops of distilled water to get a homogenous paste 14 . A plastic tool was used to inject the Simvastatin mixture into the pulp chamber, which was then compressed with a condenser.…”