Based on 2.93 fb −1 of 𝑒 + 𝑒 − collision data taken at √ 𝑠 = 3.773 GeV and 1.31×10 9 𝐽/𝜓 events taken at √ 𝑠 = 3.097 GeV, we present the searches for baryon number and lepton number violation in𝑐 𝑒 − + 𝑐.𝑐, and 𝐽/𝜓 → 𝑝𝐾 − Λ + 𝑐.𝑐 decays. No obvious signals are found and the upper limits on the branching fractions of these decays are set to be ∼ 10 −8 − 10 −6 at 90% confidence level. Those results are the most stringent ones to date for these processes but are still far above the prediction of the higher generation model.