Search for mycoplasma in synovial fluids from patients with rheumatoid arthritis.

Windsor, G. D.; Nicholls, Anne; Maini, R N; Edward, D. G. ff.; Lemcke, Ruth M.; Dumonde, D. C.

doi:10.1136/ard.33.1.70

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Rheumatoid Arthritis1

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1974

1989

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Cited by 13 publications

(2 citation statements)

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“…The failure to isolate M. fermentans is in accord with the recent negative reports of Cole, Ward and Smith (1973), and Windsor, Nicholls, Maini, Edward, Lemcke, and Dumonde (1974), who did use a preliminary gradient centrifugation, and also those of Mardh, Nilsson, and Bjelle (1973). We have no explanation for the discrepancy between the original positive reports of Williams and the negative findings in this and other studies, but the role of M. fermentans in RA must surely be regarded as 'non proven'.…”

Section: Discussionsupporting

confidence: 87%

Mycoplasmas and rheumatoid arthritis.

Stewart¹,

Duthie²,

Mackay³

et al. 1974

Annals of the Rheumatic Diseases

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Section: Discussionsupporting

confidence: 87%

Mycoplasmas and rheumatoid arthritis.

Stewart¹,

Duthie²,

Mackay³

et al. 1974

Annals of the Rheumatic Diseases

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“…The exciting findings of Williams and co-workers have unfortunately not been confirmed, although considerable effort has been expended by several experienced mycoplasmologists (165,186 …”

Section: Rheumatoid Arthritismentioning

confidence: 99%

A Reevaluation of the Role of Mycoplasmas in Human Disease

Stanbridge¹

1976

Annu. Rev. Microbiol.

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Studies on the infectious etiology of human rheumatoid arthritis

Ward

1975

Arthritis & Rheumatism

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A total of 29 rheumatoid patients and 19 nonrheumatoid patients were tested for evidence of present or past infection b y M pneumoniae, M hominis, M fermentam, M arthritidis, M pulmonis, and M hyorhinis. T h e techniques of lymphocyte transformation, metabolic-inhibiting antibody test, and mycoplasmacidal antibody test indicated no significant difference in the response of rheumatoid as opposed to nonrheumatoid patients.Although a wide variety of immunologic processes are apparent within the joints of patients exhibiting rheumatoid arthritis (RA), the nature of the initiating agent or event appears elusive. An infectious etiology for human rheumatoid arthritis remains an attractive hypothesis despite numerous conflicting and inconclusive results on the isolation of an agent.

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Search for mycoplasma in synovial fluids from patients with rheumatoid arthritis.

Cited by 13 publications

References 12 publications

Mycoplasmas and rheumatoid arthritis.

Mycoplasmas and rheumatoid arthritis.

A Reevaluation of the Role of Mycoplasmas in Human Disease

Studies on the infectious etiology of human rheumatoid arthritis

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