Search for new antimicrobials: spectroscopic, spectrometric, and in vitro antimicrobial activity investigation of Ga(III) and Fe(III) complexes with aroylhydrazones

Klarić, David; Pocrnić, Marijana; Lež, Dražen; Polović, Saša; Kontrec, Darko; Kosalec, Ivan; Budimir, Ana; Galić, Nives

doi:10.1007/s00775-022-01967-y

Cited by 2 publications

(1 citation statement)

References 36 publications

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“…From our knowledge, there are scare complex showing antibacterial, anti‐candida and anti‐dermatophytes effect. In addition, same significant activities against gram positive bacteria and Escherchia coli as well as Candida albicans were also reported by the complex Fe(III), described by Klaric et al [59] . Nevertheless, our complex was more effective, since it can be active at 5 mg/ml, unlike the complex of, [59] which need more than 10 mg/ml to be active.…”

Section: Resultssupporting

confidence: 84%

Structural Study, Spectroscopic Characterization and Evaluation of the Antimicrobial Behavior of a New Fe (III) Organic‐Inorganic Hybrid Material: (C₈H₁₄N₂)₄[(FeCl₆)(FeCl₄)]Cl₄

Essghaier,

Methamem,

Faouzi Zid

et al. 2023

ChemistrySelect

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Due to the increasing demand for novel antimicrobials agents to treat microbial infections, the current work, focused on the synthesis of new agents owing innovative chemistry and modes of action. We describe an organic‐inorganic hybrid compound with the formula (C8H14N2)4[(FeCl6)(FeCl4)]Cl4, it was synthesized via slow evaporation at room temperature, and characterized using various techniques. The compound crystallizes in the tetragonal system, with I41/a space group. In the crystal structure, the organic layers are made up of protonated m‐Xylylene diamine (C8H14N2)2+ creating between them free tunnels, in which inorganic entities can be placed. These entities contain one octahedral (FeCl6)3− ion, one tetrahedral (FeCl4)−, and uncoordinated chlorine anions. Crystal cohesion is achieved through N−H…Cl hydrogen bonds and Cl…Cl interactions. The UV‐vis spectroscopy was investigated and the optical band gap energy 2.00 eV suggests the semiconductor behavior of the title compound. The functional groups present in the crystal structure were performed by FTIR spectroscopy. Thermal analysis was also carried out. Analysis of the Hirshfeld surface revealed that the H…Cl/Cl…H interactions dominate the structure (74 %). The new Fe(III) complex gave strong antibacterial potential against S. aureus, E. coli, M. luteus, it was able to inhibit growth of Candida species and Trichophyton intergiditale and showing lysozyme activity.

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Section: Resultssupporting

confidence: 84%

Structural Study, Spectroscopic Characterization and Evaluation of the Antimicrobial Behavior of a New Fe (III) Organic‐Inorganic Hybrid Material: (C₈H₁₄N₂)₄[(FeCl₆)(FeCl₄)]Cl₄

Essghaier,

Methamem,

Faouzi Zid

et al. 2023

ChemistrySelect

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Aluminum(III) complexes of aroylhydrazones derived from nicotinic acid hydrazide: MS, UV-Vis and DFT study

Klarić,

Pilepić,

Kontrec

et al. 2024

Journal of Coordination Chemistry

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Search for new antimicrobials: spectroscopic, spectrometric, and in vitro antimicrobial activity investigation of Ga(III) and Fe(III) complexes with aroylhydrazones

Cited by 2 publications

References 36 publications

Structural Study, Spectroscopic Characterization and Evaluation of the Antimicrobial Behavior of a New Fe (III) Organic‐Inorganic Hybrid Material: (C₈H₁₄N₂)₄[(FeCl₆)(FeCl₄)]Cl₄

Structural Study, Spectroscopic Characterization and Evaluation of the Antimicrobial Behavior of a New Fe (III) Organic‐Inorganic Hybrid Material: (C₈H₁₄N₂)₄[(FeCl₆)(FeCl₄)]Cl₄

Aluminum(III) complexes of aroylhydrazones derived from nicotinic acid hydrazide: MS, UV-Vis and DFT study

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Search for new antimicrobials: spectroscopic, spectrometric, and in vitro antimicrobial activity investigation of Ga(III) and Fe(III) complexes with aroylhydrazones

Cited by 2 publications

References 36 publications

Structural Study, Spectroscopic Characterization and Evaluation of the Antimicrobial Behavior of a New Fe (III) Organic‐Inorganic Hybrid Material: (C8H14N2)4[(FeCl6)(FeCl4)]Cl4

Structural Study, Spectroscopic Characterization and Evaluation of the Antimicrobial Behavior of a New Fe (III) Organic‐Inorganic Hybrid Material: (C8H14N2)4[(FeCl6)(FeCl4)]Cl4

Aluminum(III) complexes of aroylhydrazones derived from nicotinic acid hydrazide: MS, UV-Vis and DFT study

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Product

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Structural Study, Spectroscopic Characterization and Evaluation of the Antimicrobial Behavior of a New Fe (III) Organic‐Inorganic Hybrid Material: (C₈H₁₄N₂)₄[(FeCl₆)(FeCl₄)]Cl₄

Structural Study, Spectroscopic Characterization and Evaluation of the Antimicrobial Behavior of a New Fe (III) Organic‐Inorganic Hybrid Material: (C₈H₁₄N₂)₄[(FeCl₆)(FeCl₄)]Cl₄