Hypothetical low-mass particles, such as axions, provide a compelling explanation for the dark matter in the universe. Such particles are expected to emerge abundantly from the hot interior of stars. To test this prediction, the CERN Axion Solar Telescope (CAST) uses a 9 T refurbished Large Hadron Collider test magnet directed towards the Sun. In the strong magnetic field, solar axions can be converted to X-ray photons which can be recorded by X-ray detectors. In the 2013-2015 run, thanks to low-background detectors and a new X-ray telescope, the signal-to-noise ratio was increased by about a factor of three. Here, we report the best limit on the axion-photon coupling strength (0.66 × 10 −10 GeV −1 at 95% confidence level) set by CAST, which now reaches similar levels to the most restrictive astrophysical bounds.A dvancing the low-energy frontier is a key endeavour in the worldwide quest for particle physics beyond the standard model and in the effort to identify dark matter 1,2 . Nearly massless pseudoscalar bosons, often generically called axions, are particularly promising because they appear in many extensions of the standard model. They can be dark matter in the form of classical field oscillations that were excited in the early universe, notably by the re-alignment mechanism 3 . One particularly well motivated case is the quantum chromodynamics (QCD) axion, the eponym for all such particles. The existence of this new lowmass boson follows from the Peccei-Quinn mechanism as an explanation why QCD is perfectly time-reversal invariant within current experimental precision 3 .Axions were often termed 'invisible' because of their extremely feeble interactions, yet they are the target of a fast-growing international landscape of experiments. Numerous existing and foreseen projects assume that axions are the galactic dark matter and use a variety of techniques that are sensitive to different interaction channels and optimal in different mass ranges 4 . Independently of the dark-matter assumption, one can search for new forces mediated by these low-mass bosons 5 or the back-reaction on spinning black holes (superradiance) 6 . Stellar energy-loss arguments provide restrictive limits that can guide experimental efforts, and in some cases may even suggest new loss channels 3,7,8 .The least model-dependent search strategies use the production and detection of axions and similar particles by their generic twophoton coupling. It is given by the vertex L aγ = −(1/4) g aγ F µν F µν a = g aγ E · B a, where a is the axion field, F the electromagnetic field-strength tensor, and g aγ a coupling constant of dimension (energy) −1 . Notice that we use natural units with = c = k B = 1. This vertex enables the decay a → γ γ , the Primakoff production in stars-that is, the γ → a scattering in the Coulomb fields of charged particles in the stellar plasma-and the coherent conversion a ↔ γ in laboratory or astrophysical B-fields 9,10 .The helioscope concept, in particular, uses a dipole magnet directed at the Sun to convert axions to...