Seasonal and Diurnal Fluctuations in the Concentrations of Pharmaceuticals and Personal Care Products (PPCPs) in Residential Sewage Water

Takao, Yuji; Shimazu, Miki; Fukuda, M; Ishibashi, Hiroshi; Nagae, Masaki; Kohra, Shinya; Tabira, Yasuhiro; Ishibashi, Yutaka; Arizono, Koji

doi:10.1248/jhs.54.240

Cited by 15 publications

(3 citation statements)

References 8 publications

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“…Other LoE that could be used but not implemented here include geographic variation in TCS usage based on market regions, implementation of an in‐stream decay process to account for environmental losses in the river (e.g., degradation based on aquatic aerobic half‐life), and temporal considerations. Variations in temporal emissions were not considered to be relevant given the “continuous” usage and emissions from the primary environmental source (e.g., WWTPs), although diurnal and seasonal variations in WWTP effluent concentrations have been demonstrated for other chemicals (Takao et al, 2008).…”

Section: Discussionmentioning

confidence: 99%

Applying weight of evidence methods to assessing exposure in aquatic environments: Comparing lines of evidence

Miglino

Holmes

2022

Integr Envir Assess & Manag

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Weight of evidence (WoE) is a useful approach to quantifying the relative relevance, strength, reliability, and uncertainty associated with estimates of exposure concentrations. WoE is often used in exposure assessments but rarely explored or discussed in detail. In this article, the utility of a WoE approach in aquatic exposure assessments is illustrated via two case studies using a tiered approach and the chemical triclosan. Each case study evaluates the same chemical and pathway to the environment but with substantially different data strength, reliability, and uncertainty. The collection and qualitative evaluation of relevant lines of evidence (LoE) using a three‐tiered approach are discussed. Our results demonstrate how a higher tiered WoE approach can reduce uncertainty and improve decision‐making based on predicted exposure concentrations. We also identify LoE that played a significant role in the final exposure determinations and describe a framework for conducting exposure assessments using WoE. Integr Environ Assess Manag 2022;00:1–13. © 2022 SETAC

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Section: Discussionmentioning

confidence: 99%

Applying weight of evidence methods to assessing exposure in aquatic environments: Comparing lines of evidence

Miglino

Holmes

2022

Integr Envir Assess & Manag

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“…[ 1 ] Large amounts of mefenamic acid are consumed every year due to these therapeutic properties, especially during summer. [ 2 ]…”

Section: Introductionmentioning

confidence: 99%

Elevation of antidermatophytic action of mefenamic acid by cobalt ions

AL-Janabi¹

2010

Indian J Pharmacol

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Objectives:To evaluate the antifungal property of mefenamic acid, which is a member of non-steroidal anti-inflammatory drugs (NSAIDs) group.Materials and Methods:In order to evaluate the antifungal property of mefenamic acid on dermatophytes, it was mixed with cobalt (Co) in culture media. Two species related to two genera of dermatophytes were tested for their susceptibility to mefenamic acid and its complex with Co by using colony diameter measurement method.Results:The inhibitory action of mefenamic acid on fungal strains was increased in the presence of Co. Epidermophyton floccosum showed more susceptibly to either mefenamic acid or its complex with Co than Trichophyton mentagrophytes variant mentagrophytes.Conclusions:Mefenamic acid showed potential ability to prevent growth of dermatophytes. This ability increased due to the presence of Co.

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“…[3][4][5] These emerging chemicals are currently unregulated, but their presence is of growing notoriety and concern. 6,7) They have been reported to be transported off-site via runoff and drainage.…”

Section: Introductionmentioning

confidence: 99%

Pharmaceuticals and Personal Care Products (PPCPs), and Endocrine Disrupting Compounds (EDCs) in Runoff from a Potato Field Irrigated with Treated Wastewater in Southern California

Wu²,

Chen³

et al. 2009

JOURNAL OF HEALTH SCIENCE

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Irrigation of crops with treated wastewater has been employed in many regions of the world. It mitigates the pressure of water demand, however, it also introduces effluent-derived organic contaminants into surface waters via agricultural runoff. In this study, a potato field located in southern California was selected as the research site. Runoff samples were collected during irrigation events, and a variety of compounds were identified both in irrigation water and runoff samples. Treatments on the field included polyacrylamide (PAM) application, deep plow, previous-grown Sudan grass, and control (without above treatments). The compounds included pharmaceuticals (e.g., clofibric acid, ibuprofen, naproxen, ketoprofen, diclofenac), personal care product (e.g., triclosan), endocrine disrupting compounds (e.g., bisphenol A, 4-n-nonylphenol, 4-toctylphenol), and estrogenic compounds (e.g., estrone, 17β-estradiol, 17α-ethynylestradiol). The monitoring results showed the presence of these compounds in runoff samples. They were at concentrations from below limits of quantification (LOQ) to sub µg/l levels. Although their levels were low, their potential to elicit adverse effects in aquatic organisms cannot be overlooked.

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Seasonal and Diurnal Fluctuations in the Concentrations of Pharmaceuticals and Personal Care Products (PPCPs) in Residential Sewage Water

Cited by 15 publications

References 8 publications

Applying weight of evidence methods to assessing exposure in aquatic environments: Comparing lines of evidence

Applying weight of evidence methods to assessing exposure in aquatic environments: Comparing lines of evidence

Elevation of antidermatophytic action of mefenamic acid by cobalt ions

Pharmaceuticals and Personal Care Products (PPCPs), and Endocrine Disrupting Compounds (EDCs) in Runoff from a Potato Field Irrigated with Treated Wastewater in Southern California

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