Seasonal dynamics of myocardial infarctions in regions with different types of a climate: a meta-analysis

Abstract

Background It is known that cardiovascular events (CVE) occur more often in winter than in summer. However, dependence of myocardial infarction (MI) risk of on various meteorological factors is still not fully understood. Also, the dependence of the seasonal dynamics of MI on gender and age has not yet been studied. The purpose of our meta-analysis is to reveal dependence of the circannual dynamics of MI hospitalizations on gender, age, and characteristics of a region’s climate. Main body Using Review Manager 5.3, we performed a meta-analysis of 26 publications on the seasonal dynamics of MI. In our meta-analysis, the relative MI risk was higher in colder compared to warmer seasons. Old age insignificantly increased the seasonal MI risk; gender did not affect the seasonal dynamics of MI, but MI was more common in men than in women. The severity of the seasonal dynamics of MI risk depended on the climate of the region. In a climate with a small amplitude of circannual fluctuations in air temperature, atmospheric pressure, and partial oxygen density in the air, as well as in regions where air humidity is higher in winter than in summer, an increase in MI risk in winter compared to summer was significant. It was not significant in regions with opposite climatic tendencies. Conclusions Based on the results of our studies, it can be concluded that a decrease in air temperature increases in MI risk; in addition, hypoxia in the hot season can provoke CVE associated with ischemia.

Evolução do infarto agudo do miocárdio entre 2008 e 2022

“…A relação entre o inverno e o aumento de internações por IAM é conhecida (15). Existem algumas hipóteses para explicar essa relação como, por exemplo, a temperatura baixa (16) e infecções respiratórias (17) e devemos dedicar pesquisas para esse fenômeno.…”

Non-Conventional Risk Factors: “Fact” or “Fake” in Cardiovascular Disease Prevention?

“…Conversely, males had a greater reduction in core body temperature when exposed to cold, which could explain the higher cardiovascular risk and mortality in response to the cold [ 214 ]. Despite these pathophysiological difference, a recent meta-analysis indicates that gender did not affect the seasonal dynamics of myocardial infarction, with a trend of higher susceptibility in men than in women [ 217 ].…”

“…Conversely, males had a greater reduction in core body temperature when exposed to cold, which could explain the higher cardiovascular risk and mortality in response to the cold [214]. Despite these pathophysiological difference, a recent meta-analysis indicates that gender did not affect the seasonal dynamics of myocardial infarction, with a trend of higher susceptibility in men than in women [217]. -Age: the elderly are more vulnerable to low temperatures, whose thermoregulatory capacity is often compromised (especially 65-75 or >75 years) [216,218], with exposure to heat, people > 60 years respond with less sweating, reduced blood flow to the skin, less increase in cardiac output, and less redistribution of splanchnic and renal blood flow than younger people.…”

Influence of heliogeophysical and climatic factors on the cardiovascular system: a literature review

“…Последнее десятилетие ознаменовалось появлением исследований с использованием миллионных регистров и выборок, что существенно повысило качество и уровень выполняемых работ. Во многих систематических обзорах и метаанализах определена устойчивая обратная связь J-образной формы между температурой и сердечно-сосу дистыми событиями [15][16][17][18].…”