Seasonal variability of the mutagenicity of airborne particles in the town center

Zwoździak, J.; Jadczyk, P.; Kucharczyk, J

doi:10.1016/s0021-8502(00)00082-3

Cited by 12 publications

(9 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A greater sensitivity of strain YG1024 to detect mutagenic nitroarenes was observed in other studies of different MP fractions in petrochemical industry areas (Coronas et al, 2009;Pereira, 2008;Pereira et al, 2010), evidencing the applicability of this strain to evaluating particulate matter from sites impacted by that industry type. On the other hand, strain YG1021 presented higher results compared to YG1024 in investigations of the PM of urban environments (Coronas et al, 2016;Brito et al, 2013;K€ affer et al, 2012;Silva et al, 2015;Zwozdziak et al, 2001). Considering this relationship, the results of the present study evidence a greater contribution of nitroarenes from industrial sources in the two areas evaluated.…”

Section: Discussionsupporting

confidence: 42%

“…Nitro-PAHs can be emitted directly by sources of combustion or occur as the result of secondary reactions in the atmosphere between PAHs and nitrogen oxides-NOx (Zwozdziak et al, 2001). Traversi et al (2011) found a strong correlation between the mutagenic potency of PM10 and PM2.5 and the nitrogen oxides concentrations present in the atmosphere.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Genotoxicity biomarkers for airborne particulate matter (PM2.5) in an area under petrochemical influence

Lemos

Flores

et al. 2016

Chemosphere

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 42%

Section: Discussionmentioning

confidence: 99%

Genotoxicity biomarkers for airborne particulate matter (PM2.5) in an area under petrochemical influence

Lemos

Flores

et al. 2016

Chemosphere

View full text Add to dashboard Cite

“…11 Epidemiologic studies have shown relationships between atmospheric PM concentrations and adverse health effects. [12][13][14][15][16][17][18][19][20] As a result of these studies, great interest exists within the health effects community and the regulatory community in understanding which components or physical characteristics of atmospheric PM act to cause the observed adverse health effects. It is important to note, however, that hundreds of chemical species, both organic and inorganic, can be measured in atmospheric PM.…”

Section: Introductionmentioning

confidence: 99%

The Distribution of Particle-Phase Organic Compounds in the Atmosphere and Their Use for Source Apportionment during the Southern California Children’s Health Study

Manchester-Neesvig

Schauer

Cass

2003

Journal of the Air & Waste Management Association

View full text Add to dashboard Cite

Atmospheric particulate matter (PM) samples from 12 sites in southern California, collected as part of the Southern California Children's Health Study (SCCHS), were analyzed using gas chromatography/mass spectrometry (GC/MS) techniques. Ninety-four organic compounds were quantified in these samples, including n-alkanes, fatty acids, polycyclic aromatic hydrocarbons (PAH), hopanes, steranes, aromatic diacids, aliphatic diacids, resin acids, methoxyphenols, and levoglucosan. Annual average concentrations of all detected compounds, as well as average concentrations for three seasonal periods, were determined at all 12 sites for the calendar year of 1995. These measurements provide important information about the seasonal and spatial distribution of particlephase organic compounds in southern California. Also, co-located samples from one site were analyzed to assess precision of measurement. Excellent agreement was observed between annual average concentrations for the broad range of organic compounds measured in this study. Measured concentrations from the 12 sampling sites were used in a previously developed molecularmarker source apportionment model to quantify the primary source contributions to the PM 10 organic carbon and mass concentrations at these 12 sites. Source contributions to atmospheric PM from six important air pollution sources were quantified: gasoline-powered motor vehicle exhaust, diesel vehicle exhaust, wood smoke, vegetative detritus, tire wear, and natural gas combustion. Important trends in the seasonal and spatial patterns of the impact of these six sources were observed. In addition, contributions from meat smoke were detected in selected samples.

show abstract

“…Chemically bound compounds to particulate matter such as polycyclic aromatic hydrocarbons (PAHs) and their derivatives, particularly highly condensed compounds with five or six aromatic rings, are known to be mutagenic and carcinogenic (Tuominen et al, 1988;Zwoździak et al, 2001). Some of these compounds and their mixtures can produce DNA damage, such as inducing mutations in bacterial and mammalian cells, affecting chromosomes, and causing oncogenic transformations (Lewtas, 1988(Lewtas, , 1993.…”

Section: Introductionmentioning

confidence: 99%

Assessment of mutagenicity and toxicity of different‐size fractions of air particulates from La Plata, Argentina, and Leipzig, Germany

Massolo

Müller

Tueros

et al. 2002

Environmental Toxicology

View full text Add to dashboard Cite

Airborne particulates, especially fine particles and bound chemical compounds, are a potential mediator of adverse health effects. In this study an analysis was done of the concentration and size distribution of air particulate matter, the content of bound polycyclic aromatic hydrocarbons (PAHs), and the biological effects of organic extracts from different fractions of dust that had been influenced by urban and industrial emissions from the regions of La Plata, Argentina, and Leipzig, Germany, along with samples from control areas. Air particulate matter was sampled in summer and winter in each region using a high-volume sampler with a six-stage cascade impactor, classifying dust in six size fractions from 10-microm particles to those less than 0.49 microm in size. Organic extracts of dust were tested for mutagenicity (Ames test, Salmonella typhimurium TA98 strain, S9+) and cytotoxicity (Tetrahymena pyriformis test system, growth rate, cell respiration). The content of PAHs was analyzed by high-performance liquid chromatography (HPLC) with diode array and fluorescence detection. Mutagenic and cytotoxic effects were found to be associated with very fine (<0.49 microm) and fine (<1.5 microm) particle-bound compounds, corresponding to a higher content of PAHs. The mutagenic potency (revertants/m(3)) associated with particles less than 0.49 microm from urban areas of La Plata was about 1 order of magnitude higher than in particles in the range of 3.0 to 0.49 microm. Fine fractions from sites with an industrial burden were also found to exhibit high mutagenic potency. A similar tendency was observed in cytotoxicity tests with T. pyriformis. This cell system proved to be very sensitive to toxicants in tested dust fractions. The observed biological effects were found to be correlated significantly with concentrations of total PAH, carcinogenic PAHs, and benzo[a]pyrene.

show abstract

Seasonal variability of the mutagenicity of airborne particles in the town center

Cited by 12 publications

References 25 publications

Genotoxicity biomarkers for airborne particulate matter (PM2.5) in an area under petrochemical influence

Genotoxicity biomarkers for airborne particulate matter (PM2.5) in an area under petrochemical influence

The Distribution of Particle-Phase Organic Compounds in the Atmosphere and Their Use for Source Apportionment during the Southern California Children’s Health Study

Assessment of mutagenicity and toxicity of different‐size fractions of air particulates from La Plata, Argentina, and Leipzig, Germany

Contact Info

Product

Resources

About