Seasonal variation in U.S. hospitalizations for chronic limb‐threatening ischemia

Abstract

Background: Seasonal variation in coronary artery disease is well described, with a peak in the winter and a trough in the summer. However, little is known about seasonal trends in hospital admission for critical limb-threatening ischemia (CLTI) and associated outcomes.

From respiratory diseases to nervous system disorders: Unraveling the certified causes of influenza‐associated deaths in Poland from 2000 to 2019

“…31 While the high mortality rate combined with a low number of less severe cases raises questions concerning attribution, more importantly, studies on patients with severe cardiovascular conditions show that influenza vaccination can significantly improve their prognosis 32,33 Studies on multiple unrelated conditions have demonstrated a similar pattern, with barely noticeable seasonal variability in amputation rates for critical limb-threatening ischemia, but hospitalization patterns aligning with influenza waves. 34 An elevated incidence of hospitalization for acute kidney injury was observed in winter, and during this period, the mortality rate among those hospitalized was found to be highest. 35 An increased winter mortality rate was observed in intensive care units, which remained statistically significant even after adjusting for diagnosis.…”

“…Studies on multiple unrelated conditions have demonstrated a similar pattern, with barely noticeable seasonal variability in amputation rates for critical limb‐threatening ischemia, but hospitalization patterns aligning with influenza waves. 34 An elevated incidence of hospitalization for acute kidney injury was observed in winter, and during this period, the mortality rate among those hospitalized was found to be highest. 35 An increased winter mortality rate was observed in intensive care units, which remained statistically significant even after adjusting for diagnosis.…”