Seasonal variation of P-wave dispersion in healthy subjects

Köse, Sedat; Aytemir, Kudret; Can, İlknur; İyisoy, Atilla; Kilic, Ayhan; Amasyalı, Basri; Kurşaklıoğlu, Hürkan; Işık, Ersoy; Oto, Ali̇; Demirtaş, Ertan

doi:10.1054/jelc.2002.35848

Cited by 17 publications

(14 citation statements)

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“…Pd was also similar in the two groups. The results of maximal and minimal P wave duration and Pd of the FMF patient group and the control group are similar to those published for 532 healthy individuals during spring/summer seasons [7]. During 6 months of follow-up, no case of atrial Wbrillation was documented in either group.…”

Section: Resultssupporting

confidence: 85%

P wave dispersion in familial Mediterranean fever

et al. 2010

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Familial Mediterranean fever (FMF) is a hereditary disease characterized by recurrent and self-terminated attacks of fever and polyserositis. A recent study found that FMF patients had an abnormally high P wave duration and P wave dispersion, markers for supraventricular arrhythmogenicity. The aim of our study was to further evaluate atrial dispersion in FMF patients. The study group consisted of 26 patients with uncomplicated FMF and age- and sex-matched control subjects. All participants underwent 12-lead electrocardiography under strict standards. P wave length and P wave dispersion were computed from a randomly selected beat and from an averaged beat constructed from 7 to 12 beats, included in a 10-s ECG. No statistically significant differences were found between the groups in minimal, maximal, and average P wave duration and P wave dispersion calculated either from a random beat or averaged beats. During 6 months of follow-up, no supraventricular arrhythmias were documented in either group. FMF patients who are continuously treated with colchicine and do not develop amyloidosis have normal atrial conduction parameters and therefore seemingly do not have an increased electrocardiographic risk of atrial fibrillation.

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Section: Resultssupporting

confidence: 85%

P wave dispersion in familial Mediterranean fever

et al. 2010

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“…1). 3 , 7–85 Fourteen of these articles utilized only a computer‐assisted technique for P‐wave evaluation.…”

Section: Resultsmentioning

confidence: 99%

“…However, it is noteworthy that values in the controls were similar throughout the day 8 . Also, when healthy individuals were evaluated for Pd on several occasions (i.e., during different seasons), 9 yearly results were averaged. Only studies, where mean ± SD values were presented, were included.…”

Section: Methodsmentioning

confidence: 99%

Meta‐Analysis of P‐Wave Dispersion Values in Healthy Individuals: The Influence of Clinical Characteristics

Nussinovitch¹

2012

Noninvasive Electrocardiol

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Pd, Pmax, and Pmin span a wide range of values in healthy individuals. Seemingly, abnormal values were often reported in healthy adults. The high variability of P-wave parameters in healthy individuals, and overlapping of the results with those reported for patients with increased risk for atrial fibrillation, might suggest that this technique has limited sensitivity and specificity. The variability between studies may stem from methodological issues and, therefore, there is a definite need for methodological standardization of Pd measurements.

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“…Several studies have showed that PWD has a predictive value for the development of AF in patients without apparent heart disease and in patients who were hypertensive or had various cardiac conditions 1-3. Apart from cardiovascular diseases, several conditions such as seasonal variation, alcohol intake and caffeine ingestion have been demonstrated to affect PWD 4-6. …”

Section: Introductionmentioning

confidence: 99%

The effects of iron deficiency anemia on p wave duration and dispersion

Şimşek

Güneş

Demir

et al. 2010

Clinics

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OBJECTIVES:The association between P wave dispersion and iron deficiency anemia has not been documented in the literature. In this study, we evaluated P wave dispersion in patients with iron deficiency anemia and the possible relationships between P wave dispersion and other echocardiographic parameters.INTRODUCTION:The iron status of an individual may play an important role in cardiovascular health. Anemia is an independent risk factor for adverse cardiovascular outcomes. P wave dispersion is a simple electrocardiographic marker that has a predictive value for the development of atrial fibrillation. Apart from cardiovascular diseases, several conditions, such as seasonal variation, alcohol intake and caffeine ingestion, have been demonstrated to affect P wave dispersion.METHODS:The study included 97 patients who had iron deficiency anemia and 50 healthy subjects. The cases were evaluated with a clinical examination and diagnostic tests that included 12‐lead electrocardiography and transthoracic echocardiography.RESULTS:Compared to the control group, patients with iron deficiency anemia showed significantly longer maximum P wave duration (Pmax) (91.1±18.0 vs. 85.8±6.7 msec, p = 0.054), P wave dispersion (PWD) (48.1±7.7 vs. 40.9±5.6 msec, p<0.001), mitral inflow deceleration time (DT) (197.5±27.9 vs. 178.8±8.9 msec, p<0.001) and isovolumetric relaxation time (IVRT) (93.3±9.2 vs. 77.4±8.2 msec, p<0.001); they also showed increased heart rate (85.7±16.1 vs. 69.0±4.4, p<0.001) and frequency of diastolic dysfunction (7 (7.2%) vs. 0). Correlation analysis revealed that PWD was significantly correlated with IVRT, DT, heart rate, the presence of anemia and hemoglobin level.CONCLUSIONS:Iron deficiency anemia may be associated with prolonged P wave duration and dispersion and impaired diastolic left ventricular filling.

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Seasonal variation of P-wave dispersion in healthy subjects

Cited by 17 publications

References 0 publications

P wave dispersion in familial Mediterranean fever

P wave dispersion in familial Mediterranean fever

Meta‐Analysis of P‐Wave Dispersion Values in Healthy Individuals: The Influence of Clinical Characteristics

The effects of iron deficiency anemia on p wave duration and dispersion

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