Seasonal Variations in the Rupture of Abdominal Aortic Aneurysms.

Manfredini, Roberto; Portaluppi, Francesco; Gallerani, Massimo; Tassi, Adriana; Salmi, Raffaella; Zamboni, Paolo; Chierici, F; Occhionorelli, Savino; Mascoli, Francesco; Rizzioli, Emanuela; Liboni, A; Donini, I.; Fersini, C

doi:10.1536/ihj.38.67

Cited by 18 publications

(12 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Similar to the present fi ndings, nonlinear Fourier rhythm analysis in a study by Mehta et al [21] identifi ed signifi cant (p = .022) monthly (seasonal) variations in the occurrence of acute aortic dissection with a peak in the month of January. While, rhythm analysis of monthly distribution in a study by Manfredini et al [16] enrolling only 54 patients with RAAA demonstrated a signifi cant (p = 0.024) pattern characterized by a six-month period with two peaks occurring in April and October.…”

Section: Discussionmentioning

confidence: 92%

“…Of 164 potentially relevant articles screened initially, we identifi ed 14 eligible studies [7][8][9][10][11][12][13][14][15][16][17][18][19][20] enrolling a total of 3,798 patients with RAAA (Table I).…”

Section: Resultsmentioning

confidence: 99%

“…Three studies [8,12,18] enrolled exclusive patients with operated RAAA. Studies were performed in various countries, such as Australia [8], France [9], Germany [7], Greece [15,20], Ireland [11], Italy [16], Sweden [19], Turkey [13], and the United Kingdom [10,12,14,17,18]. Despite the noted heterogeneity in design among the included studies, there was suffi cient similarity between the populations and the hypotheses to merit inclusion of all 14 studies in the quantitative meta-analysis.…”

Section: Limitationsmentioning

confidence: 99%

See 2 more Smart Citations

A meta-analysis of monthly variation in occurrence of abdominal aortic aneurysm rupture

Takagi

Ando

Umemoto

2017

Vasa

View full text Add to dashboard Cite

Summary:Background: We performed a meta-analysis to assess the presence of an annual rhythmic variability of ruptured abdominal aortic aneurysm (RAAA) onset. Patients and methods: Eligible studies were observational studies enrolling patients with RAAA and reporting monthly incidence of RAAA. Study-specifi c estimates, i. e. monthly incidence of RAAA, were combined using the random-effects model. Chronobiological analysis was performed by applying a partial Fourier series to pooled monthly incidence by using the weighted least-squares method. Results: We identifi ed 14 eligible studies enrolling a total of 3,798 patients with RAAA. Pooled monthly incidence of RAAA was 8.7 % in January, 7.7 % in February, 8.7 % in March, 7.3 % in April, 7.8 % in May, 7.2 % in June, 7.0 % in July, 7.0 % in August, 8.1 % in September, 8.8 % in October, 8.4 % in November, and 8.3 % in December. Chronobiological analysis identifi ed a signifi cant (p = 0.0020) annual pattern in the occurrence of RAAA with a peak in December to January and a nadir in June to July. Pooled analysis demonstrated signifi cantly more incidence in December than in June (p = 0.03) as well as in January than in July (p = 0.05). Conclusions: A signifi cant annual pattern in the occurrence of RAAA with a peak in December to January and a nadir in June to July was identifi ed with signifi cantly more incidence in December than in June and in January than in July. Keywords:Abdominal aortic aneurysm, meta-analysis, monthly variation, rupture ever, is suggested to be distinct from that of aortic dissection. Synchronous existence of AAA and AAD is believed to be rare [5], and AAD develops in the absence of a preexisting aortic aneurysm in most (> 80 %) cases [6]. Mechanisms for the rupture of AAAs and those for onset of aortic dissection may be not the same. In this article, we performed a meta-analysis to assess the presence of an annual rhythmic variability of exclusive RAAA onset. Materials and methodsAll studies investigating monthly incidence of RAAA were identifi ed using a 2-level search strategy. First, databases including MEDLINE and EMBASE were searched through March 2017 using web-based search engines (PubMed and OVID). Second, relevant studies were identifi ed through a manual search of secondary sources including references of initially identifi ed articles and a search of reviews and commentaries. All references were downloaded for consolidation, elimination of duplicates,

show abstract

Section: Discussionmentioning

confidence: 92%

Section: Resultsmentioning

confidence: 99%

Section: Limitationsmentioning

confidence: 99%

See 1 more Smart Citation

A meta-analysis of monthly variation in occurrence of abdominal aortic aneurysm rupture

Takagi

Ando

Umemoto

2017

Vasa

View full text Add to dashboard Cite

show abstract

“…The incidence of RAAA exhibits a well-documented winter-spring peak [3][4][5][6][7][8][9]. Atmospheric pressure changes reflect such a pattern and may explain this temporal phenomenon.…”

Section: Discussionmentioning

confidence: 99%

“…Many investigators have demonstrated a seasonal variation in the incidence of ruptured abdominal aortic aneurysm (RAAA), with a preponderance of such events occurring in the winter and spring months (although there is no consensus on the month of peak rupture) [3][4][5][6][7][8][9]. Atmospheric pressure, being lower in the winter months, is one meteorological variable, which mirrors this pattern [10].…”

Section: Introductionmentioning

confidence: 99%

Atmospheric pressure variations and abdominal aortic aneurysm rupture

et al. 2008

View full text Add to dashboard Cite

show abstract

Seasonal incidence of ruptured abdominal aortic aneurysm and the influence of atmospheric pressure: a systematic review and meta-analysis

Zhou

et al. 2018

Int J Biometeorol

View full text Add to dashboard Cite

Ruptured abdominal aortic aneurysm (rAAA) is a life-threatening condition with a high mortality rate. Seasonal variations in the incidence of rAAA and the influence of atmospheric pressure have been studied throughout decades; however, the conclusions are contradictory. Therefore, we aimed to conduct a meta-analysis and systematic review of literature on seasonal variations in rAAA incidence and the influence of atmospheric pressure. Studies investigating seasonal variations in rAAA incidence and influence of atmospheric pressure were retrieved. For dichotomous data, we generated risk ratios (RRs) and 95% confidence intervals (CIs) for rAAA incidence compared among seasons. The studies were subdivided according to latitude, elevation, and climatic types, for subgroup comparisons. Studies reporting monthly incidence and seasonal mortality were further investigated. For continuous data, standardized mean differences (SMDs) and 95% CIs were generated for atmospheric pressure comparisons. Twenty-four eligible studies were included, comprising a total of 38,506 patients with rAAA. Pooled rAAA incidence was 25% in spring, 23% in summer, 26% in autumn, and 26% in winter. Pooled analysis demonstrated a statistically significant higher rAAA incidence in winter than in summer (RR 1.10, P = 0.04) and in autumn than in summer (RR 1.11, P < 0.00001). However, there was no statistically significant difference among other seasons. In the study of the influence of atmospheric pressure, no statistically significant difference was observed. In conclusion, our study revealed a higher incidence of rAAA in autumn and winter than in summer; however, atmospheric pressure was found to exert no influence.

show abstract

Seasonal Variations in the Rupture of Abdominal Aortic Aneurysms.

Cited by 18 publications

References 19 publications

A meta-analysis of monthly variation in occurrence of abdominal aortic aneurysm rupture

A meta-analysis of monthly variation in occurrence of abdominal aortic aneurysm rupture

Atmospheric pressure variations and abdominal aortic aneurysm rupture

Seasonal incidence of ruptured abdominal aortic aneurysm and the influence of atmospheric pressure: a systematic review and meta-analysis

Contact Info

Product

Resources

About