Seasonality in the Volatile Oil Composition of Green Propolis from the Caatinga Biome

Mendonça, Lavosyer da Silva; Frota, Vanessa Moreira; Pinto, Barbara Juliete Freire; Moita, Emanuella Cristine dos Santos; Hora, João Pedro da; Costa, Mikaele Fernandes; Fernandes, Jorge Alberto Bezerra; Zocolo, Guilherme Julião; Gomes, Geovany Amorim; Vale, Jean Parcelli Costa do; Bandeira, Paulo Nogueira; Santos, Hélcio Silva dos; Rodrigues, Sueli

doi:10.1007/s43450-021-00186-x

Cited by 5 publications

(1 citation statement)

References 24 publications

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“…is a shrubby tree of the genus Mimosa (family Fabaceae) that is naturally present in the entire northeastern Brazilian Caatinga biome, including the beekeeping industry. Bees use salivary enzymes to chop up pieces of shoot apices and combine them with wax, thus producing the green-colour propolis of Caatinga [7].…”

Section: Introductionmentioning

confidence: 99%

Vasorelaxant Activity of (2S)-Sakuranetin and Other Flavonoids Isolated from the Green Propolis of the Caatinga Mimosa tenuiflora

Son,

Gianibbi,

Panti

et al. 2024

Planta Med

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Some in vitro and in vivo evidence is consistent with the cardiovascular beneficial activity of propolis. As the single actors responsible for this effect have never been identified, an in-depth investigation of flavonoids isolated from the green propolis of the Caatinga Mimosa tenuiflora was performed and their mechanism of action was described. A comprehensive electrophysiology, functional, and molecular docking approach was applied. Most flavanones and flavones were effective CaV1.2 channel blockers with a potency order of (2S)-sakuranetin > eriodictyol-7,3′-methyl ether > quercetin 3-methyl ether > 5,4′-dihydroxy-6,7-dimethoxyflavanone > santin > axillarin > penduletin > kumatakenin, ermanin and viscosine being weak or modest stimulators. Except for eriodictyol 5-O-methyl ether, all the flavonoids were also effective spasmolytic agents of vascular rings, kumatakenin and viscosine also showing an endothelium-dependent activity. (2S)-Sakuranetin also stimulated KCa1.1 channels both in single myocytes and vascular rings. In silico analysis provided interesting insights into the mode of action of (2S)-sakuranetin within both CaV1.2 and KCa1.1 channels. The green propolis of the Caatinga Mimosa tenuiflora is a valuable source of multi-target vasoactive flavonoids: this evidence reinforces its nutraceutical value in the cardiovascular disease prevention arena.

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Section: Introductionmentioning

confidence: 99%

Vasorelaxant Activity of (2S)-Sakuranetin and Other Flavonoids Isolated from the Green Propolis of the Caatinga Mimosa tenuiflora

Son,

Gianibbi,

Panti

et al. 2024

Planta Med

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Northeastern Caatinga Green Propolis: Volatile Oil and Antimicrobial Activity

Son,

Ribeiro,

Teixeira

et al. 2023

Chem Nat Compd

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Bee Species, Botanical Sources and the Chemical Composition of Propolis from Yucatan, Mexico

et al. 2023

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Propolis is used by corbiculated bees to protect the bee hive; it is mostly used to seal cracks, to reduce or prevent microbial growth and to embalm invaders. Different factors have been reported to influence the chemical composition of propolis, including bee species and the flora surrounding the hive. Nevertheless, the majority of the studies are focused on propolis produced by Apis mellifera, while studies on the chemical composition of propolis produced by stingless bees are still limited. In this investigation, the chemical composition of 27 propolis samples collected in the Yucatan Peninsula from A. mellifera beehives, together with 18 propolis samples from six different species of stingless bees, were analyzed by GC-MS. Results showed that lupeol acetate and β-amyrin were the characteristic triterpenes in propolis samples from A. mellifera, while grandiflorenic acid and its methyl ester were the main metabolites present in samples from stingless bees. Multivariate analyses were used to explore the relationship between bee species and botanical sources on the chemical composition of the propolis samples. Differences in body size and, therefore, foraging abilities, as well as preferences for specific botanical sources among bee species, could explain the observed variation in propolis chemical composition. This is the first report on the composition of propolis samples from the stingless bees Trigona nigra, Scaptotrigona pectoralis, Nannotrigona perilampoides, Plebeia frontalis and Partamona bilineata.

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Seasonality in the Volatile Oil Composition of Green Propolis from the Caatinga Biome

Cited by 5 publications

References 24 publications

Vasorelaxant Activity of (2S)-Sakuranetin and Other Flavonoids Isolated from the Green Propolis of the Caatinga Mimosa tenuiflora

Vasorelaxant Activity of (2S)-Sakuranetin and Other Flavonoids Isolated from the Green Propolis of the Caatinga Mimosa tenuiflora

Northeastern Caatinga Green Propolis: Volatile Oil and Antimicrobial Activity

Bee Species, Botanical Sources and the Chemical Composition of Propolis from Yucatan, Mexico

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