“…In terms of stable isotope and trace element research, some researchers have moved away from the traditional bulk sampling approaches that see entire teeth and/or tooth crowns destroyed, and toward other techniques which are less destructive. Some of these techniques may involve mechanical grinding and drilling of small areas within a sample (Hufthammer et al 2010), or acid dissolution of successive layers of tissue. While chemical analyses such as electron probe x-ray microanalysis (EPXMA), secondary ion mass spectrometry (SIMS), proton-induced x-ray emission spectroscopy (PIXE), or synchrotron x-ray fluorescence (sXRF), have all been applied to the analysis of the chemical composition of dental tissues, laser ablation-inductively coupled plasma -mass spectrometry (LA-ICP-MS) is the most commonly utilized technique for conducting microspatial analyses of dental hard tissues (Lochner et al 1999;Goodman et al 2003;Kang et al 2004;Grün et al 2008;Humphrey et al 2008;Dolphin and Goodman 2009;Hare et al 2011;Vašinová Galiová et al 2012;Austin et al 2013;Farell et al 2013 analyses, pollutant exposure data gathered using trace element analyses (LA-ICP-MS), assessment of tissue preservation using Fourier transform infrared spectroscopy (FTIR), and isotopic analyses of δ 18 O and δ 13 C contributed data regarding origins/migration and palaeodiet, respectively.…”