Seasonality of presentation of cutaneous melanoma, squamous cell cancer and basal cell cancer in the Oxford Region

Swerdlow, Anthony

doi:10.1038/bjc.1985.274

Cited by 37 publications

(39 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Previous studies indicated that MM diagnosis was possibly influenced by seasonal fluctuations [5,6,7,8,9,10,11]. In a global assessment, a bimodal distribution indicated peaks of incidence in late spring/early summer and in autumn.…”

Section: Discussionmentioning

confidence: 99%

“…The term chronomics was coined to refer to timing and rhythm influences on cancer biology [2,3,4]. Another different and probably unrelated feature is represented by seasonality in skin cancer detection that has previously been suggested in Westernized populations [5,6,7,8,9,10,11]. In these studies, the diagnosis of cutaneous malignant melanoma (MM) appeared more frequent in late spring/early summer [5,7,8,9,10] and also in autumn [6, 9].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Space-Time Clustering and Seasonality in Diagnosing Skin Cancers in Wallonia (South-East Belgium)

Quatresooz¹,

Piérard‐Franchimont

Pierard

2008

Dermatology

View full text Add to dashboard Cite

Background: In Westernized populations, the number of diagnosed cases of primary cutaneous cancers, particularly malignant melanomas and basal cell carcinomas (BCC), has been previously shown to fluctuate during specific periods of the year. Objective and Method: The aim of the present 6-year study was to explore the seasonality if any in skin cancer detection in Wallonia (south-east Belgium). Results: For both malignant melanomas and BCC late spring/early summer and mid-autumn were the periods of highest diagnosis prevalence irrespective of gender. The amplitude of this bimodal evolution remained within the range of 2 standard deviations around the monthly means. Similar seasonal variations were also found in non-neoplastic controls consisting of laboratory samplings of onychomycoses and non-infectious onychodystrophies. Conclusion: There is reason to believe that this timing and rhythm is unrelated to any specific cancer chronomics. Rather, the present findings suggest unspecific seasonality in diagnosing skin disorders including malignancies. A variable patient awareness of changing aspects of the skin according to seasons probably represents the major influence of the described space-time clustering of skin cancer diagnosis.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Space-Time Clustering and Seasonality in Diagnosing Skin Cancers in Wallonia (South-East Belgium)

Quatresooz¹,

Piérard‐Franchimont

Pierard

2008

Dermatology

View full text Add to dashboard Cite

show abstract

“…Studies of the monthly incidence of ocular melanoma in other populations have also reported little or no similarity to cutaneous melanoma. Swerdlow found no statistical evidence of seasonality of ocular melanoma incidence among males or females in Oxford, UK, in contrast to a later report on cutaneous melanoma in that region (Swerdlow, 1983(Swerdlow, , 1985. In a study of 238 cases of ocular melanoma reported to the New York State tumour registry between 1975 and 1979 and aggregated into six two-month periods, a peak in the incidence was found in May-June for males and September-October for females (Polednak, 1985).…”

mentioning

confidence: 61%

Absence of seasonal variation in the diagnosis of melanoma of the eye in the United States

Schwartz

Weiss²

1988

Br J Cancer

View full text Add to dashboard Cite

“…Regarding seasonal variations, higher incidence of female breast cancer has been reported for the spring and summer (Cohen et al, 1983;Mason et al, 1985), and circannual contrasts have also been found for other tumours (Newell et al, 1985;Swerdlow, 1985; Hermida and Ayala, 1996). As for the thyroid, some studies have reported seasonal variations in endocrine parameters, with variables such as T3, T4 and thyroid-stimulating hormone (TSH) being higher in the autumn or winter (Halberg et al, 1981;Nicolau et al, 1987;Haus et al, 1988).…”

mentioning

confidence: 99%

Seasonal variations in the presentation and growth of thyroid cancer

Akslen

Rb²

1998

Br J Cancer

View full text Add to dashboard Cite

Summary Seasonal variation has been described in the presentation and growth of several malignant tumours, including cancers of the breast, uterus, uterine cervix, urinary bladder, liver, lymphatic system and skin, although the mechanisms are not known. We herein describe a circannual rhythm for thyroid cancer (total = 2627), with significantly more cases presenting during the late autumn and winter. In a subset of these cases (127 papillary carcinomas), significant seasonal variations with highest values in autumn-winter were found for tumour diameter and proliferation indicators (S-and G2M-phase fractions). These results indicate the likelihood of a seasonal factor (or factors) of importance for the regulation and modification of tumour cell proliferation. When further clarified, this might be of relevance for the planning of diagnostic and therapeutic strategies.Keywords: thyroid cancer; season; tumour diameter; proliferation; %S-phase-%G2M-phase Biological rhythms, especially circadian (24 h) and circannual (12 months), have been found in a wide range of physiological parameters and normal tissues (Aschoff, 1981; Shifrine et al, 1982;Halberg et al, 1983;Lerum et al, 1988;Sothem et al, 1995). Regarding seasonal variations, higher incidence of female breast cancer has been reported for the spring and summer (Cohen et al, 1983;Mason et al, 1985), and circannual contrasts have also been found for other tumours (Newell et al, 1985;Swerdlow, 1985; Hermida and Ayala, 1996). As for the thyroid, some studies have reported seasonal variations in endocrine parameters, with variables such as T3, T4 and thyroid-stimulating hormone (TSH) being higher in the autumn or winter (Halberg et al, 1981;Nicolau et al, 1987;Haus et al, 1988). As seasonal variations might be of potential interest for the detection and management of thyroid carcinomas, we wanted to review this group of tumours, most of which are slowly growing and have a good prognosis. MATERIALS AND METHODS PatientsDuring the period 1970-85, 2627 patients with thyroid cancer were reported to the Cancer Registry of Norway. Of these, 10% (n = 263) were surgically treated at the Department of Surgery, Haukeland University Hospital, in the period 1971-85. There were no major differences in the distribution of sex, age and histological types between our hospital cases and cases in the population-based Cancer Registry (Akslen and Myking, 1992 subtyping of malignant tumours according to the 1988 WHO criteria, 127 of these cases were found to represent papillary thyroid carcinomas with a diameter greater than 10 mm (microcarcinomas < 10 mm were excluded). These 127 cases were included for further studies of seasonal variations with reference to time (month) of diagnosis, largest diameter of the primary tumour and proliferation indicators (S-phase and G2M-phase fractions). Most of these patients (93%) were treated with total or near-total thyroidectomy. Regarding time of diagnosis, the date of initial histological/cytological diagnosis was used for both the registry (n = 26...

show abstract

Seasonality of presentation of cutaneous melanoma, squamous cell cancer and basal cell cancer in the Oxford Region

Cited by 37 publications

References 23 publications

Space-Time Clustering and Seasonality in Diagnosing Skin Cancers in Wallonia (South-East Belgium)

Space-Time Clustering and Seasonality in Diagnosing Skin Cancers in Wallonia (South-East Belgium)

Absence of seasonal variation in the diagnosis of melanoma of the eye in the United States

Seasonal variations in the presentation and growth of thyroid cancer

Contact Info

Product

Resources

About