Seaweeds from Halimeda Genus as Sources of Natural Antioxidants

Silva, Ana Mara de Oliveira; Novoa, Alexis Vidal; Gutierrez, Daylín Díaz; Mancini‐Filho, Jorge

doi:10.15406/japlr.2017.05.00158

Cited by 4 publications

(2 citation statements)

References 36 publications

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“…Extracts from Halimeda spp. (Figure 20c) have exhibited antibacterial effects against various pathogens, including S. aureus and Streptococcus mutans [87,88]. The antimicrobial activity is attributed to the presence of compounds like halimedatetraacetate [89].…”

Section: Antimicrobial and Antiviral Activitymentioning

confidence: 99%

Harnessing the power of seaweed: unveiling the potential of marine algae in drug discovery

Pereira,

Valado

2023

Explor Drug Sci

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Seaweeds, also known as marine algae, have gained attention as a promising source of bioactive compounds with potential applications in drug discovery. This review explores the emerging field of seaweed-based drug discovery and highlights the diverse range of bioactive compounds found in seaweeds, including polysaccharides, phlorotannins, pigments, and peptides. These compounds exhibit various pharmacological activities such as antioxidant, anti-inflammatory, antimicrobial, antiviral, and anticancer effects. Seaweeds have demonstrated particular promise in the areas of cancer research, with certain species showing potent antitumor properties. Additionally, their anti-inflammatory, antimicrobial, and neuroprotective potential has captured scientific interest in the treatment of chronic diseases and neurodegenerative disorders. However, challenges related to compound identification, extraction methods, scalability of seaweed cultivation, and understanding the mechanisms of action still need to be addressed. As researchers employ advanced technologies and dive deeper into the chemical composition of seaweeds, the untapped potential of these marine organisms in drug discovery awaits further exploration and holds significant promise for future therapeutic advancements.

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Section: Antimicrobial and Antiviral Activitymentioning

confidence: 99%

Harnessing the power of seaweed: unveiling the potential of marine algae in drug discovery

Pereira,

Valado

2023

Explor Drug Sci

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“…Works of literature reported that Halimeda spp. has potential apoptosis, anti-inflammatory, antioxidant, neuroprotective and hepatoprotective properties [7]. Spyridia hypnoides, belonging to the family Spyridiaceae, is a 15 cm tall plant like organism with numerous branches at short intervals.…”

Section: Introductionmentioning

confidence: 99%

In Vitro Enzyme Inhibitory Properties, Secondary Metabolite Profiles and Multivariate Analysis of Five Seaweeds

et al. 2020

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Seaweeds have been exploited as both food products and therapeutics to manage human ailments for centuries. This study investigated the metabolite profile of five seaweeds (Halimeda spp., Spyridia hypnoides (Bory de Saint-Vincent) Papenfuss, Valoniopsis pachynema (G. Martens) Børgesen, Gracilaria fergusonii J. Agardh and Amphiroa anceps (Lamarck) Decaisne using ultra-high-performance liquid chromatography coupled with electrospray ionization mass spectrometry (UHPLC-ESI-MS/MS). Furthermore, these seaweeds were assessed for antioxidant and inhibitory effects against α-amylase, α-glucosidase, acetyl-cholinesterase (AChE), butyryl-cholinesterase (BChE) and tyrosinase. Valoniopsis pachynema and A. anceps yielded the highest flavonoid (4.30 ± 0.29 mg RE/g) and phenolic content (7.83 ± 0.08 mg RE/g), respectively. Additionally, A. anceps exhibited significant antioxidant properties with all assays and significantly depressed BChE (IC50 = 6.68 ± 0.83 mg/mL) and α-amylase activities (IC50 = 5.34 ± 0.14 mg/mL). Interestingly, the five seaweeds revealed potent inhibitory effects against tyrosinase activity. In conclusion, A. anceps might be considered as a key source of phytoantioxidants and a potential candidate to develop nutritional supplements. Besides, the five tested seaweeds warrant further study and may be exploited as promising natural sources for managing hyperpigmentation.

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Chemical profiling of marine seaweed Halimeda gracilis using UPLC-ESI-Q-TOF-MSE and evaluation of anticancer activity targeting PI3K/AKT and intrinsic apoptosis signaling pathway

Ramalingam

Kumar

Mohan

et al. 2022

Food Research International

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Seaweeds from Halimeda Genus as Sources of Natural Antioxidants

Cited by 4 publications

References 36 publications

Harnessing the power of seaweed: unveiling the potential of marine algae in drug discovery

Harnessing the power of seaweed: unveiling the potential of marine algae in drug discovery

In Vitro Enzyme Inhibitory Properties, Secondary Metabolite Profiles and Multivariate Analysis of Five Seaweeds

Chemical profiling of marine seaweed Halimeda gracilis using UPLC-ESI-Q-TOF-MSE and evaluation of anticancer activity targeting PI3K/AKT and intrinsic apoptosis signaling pathway

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