Sebaceous Gland Carcinoma of the Scalp: Case Report and Review of the Literature

Rizvi, Murtaza; Jesus, Ramon De; Girotto, John A.; Nonaka, Daisuke; Goldberg, Nelson H.

doi:10.2310/7070.2003.35332

Cited by 2 publications

(2 citation statements)

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“…Sebaceous gland cancer is thought to arise de novo and not from benign sebaceous precursor lesions [ 6 ]. In theory, sebaceous carcinoma can occur anywhere where sebaceous glands are located.…”

Section: Discussionmentioning

confidence: 99%

A Patient with Giant Rippled-Pattern Sebaceoma in the Occipital Region

et al. 2016

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A 72-year-old male visited a nearby hospital with a large tumor in his occipital region, which had existed since 20 years. Since malignant tumor was suspected, he was referred to our department. At the initial consultation, an elastic-hard, yellow-brown, sessile tumor, measuring 8 × 7 × 5 cm and with a flat surface, was observed in the occipital region. The tumor was resected and covered with artificial dermis. Histopathologically, the lesion was composed of basal-cell-like cells with nest formation in the dermis. A rippled pattern, or the single-line arrangement of tumor cells involving the stroma, was present. In addition, some tumor clusters revealed the differentiation to sebaceous glands, and these cells were positive for cytokeratin (AE1/AE3) and epithelial membrane antigen, which is consistent with the staining of sebaceous glands. On the contrary, tumor cells were negative for epithelial antigen (Ber-EP4), and Ki67 (MIB1) index was 5% or lower. Therefore, we diagnosed the tumor as rippled-pattern sebaceoma and not as basal cell carcinoma. Although this case was quite unique in its large size, immunostaining was useful for the definite diagnosis.

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Section: Discussionmentioning

confidence: 99%

A Patient with Giant Rippled-Pattern Sebaceoma in the Occipital Region

et al. 2016

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“…Sebaceous carcinoma of the scalp is rare, with very few cases reported in literature [ 1 ]. Radiotherapy has historically been proven an effective method for local treatment of sebaceous carcinoma, especially when surgery is not recommended [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

Target splitting non-coplanar RapidArc radiation therapy for a diffuse sebaceous carcinoma of the scalp: a novel delivery technique

Xiao

et al. 2014

Radiat Oncol

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Background and purposeTo compare conventional lateral photon-electron, fixed-beam intensity modulated radiation therapy (IMRT), coplanar and non-coplanar RapidArc for the treatment of a diffuse sebaceous gland carcinoma of the scalp.MethodsComprehensive dosimetry comparisons were performed among 3D-CRT, IMRT and various RapidArc plans. Target coverage, conformity index (CI), homogeneity index (HI) and doses to organs at risk (OAR) were calculated. Monitor unites (MUs) and delivery time of each treatment were also recorded to evaluate the execution efficiency. The influence of target splitting technique and non-coplanar planning on plan quality was discussed.ResultsIMRT was superior to 3D-CRT concerning targets’ coverage at the sacrifice of larger irradiated brain volumes to low doses. CIs and HIs were better in coplanar RapidArc and non-coplanar RapidArc plans than 3D-CRT and IMRT. Best dose coverage and sparing of OARs were achieved in non-coplanar plans using target splitting technique. Treatment delivery time was longest in the IMRT plan and shortest in the coplanar RapidArc plan without target splitting. The 3%/3 mm gamma test pass rates were above 95% for all the plans.ConclusionsTarget splitting technique and non-coplanar arcs are recommended for total scalp irradiation.

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Sebaceous Gland Carcinoma of the Scalp: Case Report and Review of the Literature

Cited by 2 publications

References 0 publications

A Patient with Giant Rippled-Pattern Sebaceoma in the Occipital Region

A Patient with Giant Rippled-Pattern Sebaceoma in the Occipital Region

Target splitting non-coplanar RapidArc radiation therapy for a diffuse sebaceous carcinoma of the scalp: a novel delivery technique

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