Seborrheic dermatitis in patients with acquired immunodeficiency syndrome

Mathes, Barbara; Douglass, Margaret

doi:10.1016/s0190-9622(85)70243-5

Cited by 193 publications

(66 citation statements)

References 12 publications

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“…22 Increasing awareness about dryness and seborrhoeic dermatitis have led to patients taking better care of their skin and scalp have possibly contributed to lesser incidence seen in our study.…”

Section: Interesting Findings Of the Studymentioning

confidence: 65%

Cutaneous manifestations of HIV—a detailed study of morphological variants, markers of advanced disease, and the changing spectrum

Vasudevan¹,

Sagar

Bahal

et al. 2012

Medical Journal Armed Forces India

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. All HIV-positive patients attending outpatient departments (OPDs) and admitted as inpatients during the above period were included in the study. Initial screening for HIV was done by the rapid test and, if positive, was confirmed by two different types of enzyme-linked immunosorbent assay (ELISA). Patients already on anti-retroviral therapy (ART) were not included. Age, weight, probable time of first high-risk behaviour and CD4+ counts were noted. A complete medical history and physical examination of patients was carried out for optimal evaluation and diagnosis of dermatological and venereological lesions. The diagnosis was based on clinical criteria in most of the cases. Appropriate laboratory tests like scraping for fungus/candida, culture, skin biopsy, Cutaneous manifestations of HIV-a detailed study of morphological variants, markers of advanced disease, and the changing spectrum RESULTSInfections were the most common group of mucocutaneous manifestations, while onychomycosis was the commonly observed individual manifestation. A different set of cutaneous markers for advanced HIV disease was observed and new parameters for therapy were also arrived at. MJAFI 2012;68:20-27 CONCLUSION

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Section: Interesting Findings Of the Studymentioning

confidence: 65%

Cutaneous manifestations of HIV—a detailed study of morphological variants, markers of advanced disease, and the changing spectrum

Vasudevan¹,

Sagar

Bahal

et al. 2012

Medical Journal Armed Forces India

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“…Seborrhoic dermatitis is one of the common noninfectious skin conditions in India, with a prevalence rate of 8% to 21% in HIV positive patients [8]. This is an entity which is characterized by erythema and scaling of the central part of the face, which involves the nasolabial folds and the eyebrows, as well as the scalp [24].…”

Section: Resultsmentioning

confidence: 99%

Skin and Mucocutaneous Manifestations: Useful Clinical Predictors of HIV/AIDS

Chopra

Arora²

2012

JCDR

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Background and Aims:The HIV infection is associated with several dermatological conditions which may be the first pointer towards the existence of HIV. These may present with unusual and atypical manifestations in the course of the HIV infection. Keeping this in mind, the seroprevalence of HIV in these persons and the spectrum of the skin and the mucocutaneous lesions in the HIV positive patients was studied. Methods:The current prospective study was conducted over a period of 3 years (2006)(2007)(2008). A total of 604 persons who had any kind of skin and mucocutaneous infections were screened for the HIV infection as per the NACO guidelines after recording their clinical and epidemiological profiles.

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“…The higher incidence of Malassezia-associated dermatoses in patients with cellular immunodeficiencies suggests that cellular immunity is also important in maintaining the organism as a commensal. The incidence of PV is known to be increased in renal transplant recipients (228,391) and patients receiving steroids (57); folliculitis is seen in bone marrow transplant recipients (74), and the incidence of SD is very high in patients with AIDS (92,119,141,275,298,408,451). Despite this, only one small study has characterized the cellular immune response to Malassezia at various ages.…”

Section: Cellular Immune Responses To Malassezia In Normal Individualsmentioning

confidence: 99%

“…Lesions of SD occur primarily on the eyebrows, nasolabial folds, cheeks, and sternal and interscapular region (337). In the normal population, the incidence of SD is around 1 to 3% (155,352), but in patients who are human immunodeficiency virus positive or have AIDS-related complex or AIDS, the incidence is much higher, ranging from 30 to 83% (92,119,141,275,408), although the incidence of all opportunistic infections has decreased since the widespread use of highly active antiretroviral therapy (323). SD also has a higher than expected incidence in patients with PV (134), Parkinson's disease (55), spinal injuries (471), or depression (266) or those receiving PUVA treatment (434).…”

Section: Seborrheic Dermatitis and Dandruffmentioning

confidence: 99%

Immunology of Diseases Associated withMalasseziaSpecies

2002

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SUMMARY Malassezia species are members of the human cutaneous commensal flora, in addition to causing a wide range of cutaneous and systemic diseases in suitably predisposed individuals. Studies examining cellular and humoral immune responses specific to Malassezia species in patients with Malassezia-associated diseases and healthy controls have generally been unable to define significant differences in their immune response. The use of varied antigenic preparations and strains from different Malassezia classifications may partly be responsible for this, although these problems can now be overcome by using techniques based on recent work defining some important antigens and also a new taxonomy for the genus. The finding that the genus Malassezia is immunomodulatory is important in understanding its ability to cause disease. Stimulation of the reticuloendothelial system and activation of the complement cascade contrasts with its ability to suppress cytokine release and downregulate phagocytic uptake and killing. The lipid-rich layer around the yeast appears to be pivotal in this alteration of phenotype. Defining the nonspecific immune response to Malassezia species and the way in which the organisms modulate it may well be the key to understanding how Malassezia species can exist as both commensals and pathogens.

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Seborrheic dermatitis in patients with acquired immunodeficiency syndrome

Cited by 193 publications

References 12 publications

Cutaneous manifestations of HIV—a detailed study of morphological variants, markers of advanced disease, and the changing spectrum

Cutaneous manifestations of HIV—a detailed study of morphological variants, markers of advanced disease, and the changing spectrum

Skin and Mucocutaneous Manifestations: Useful Clinical Predictors of HIV/AIDS

Immunology of Diseases Associated withMalasseziaSpecies

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