Seborrheic Dermatitis Induced Koebnerization: A Probable Outcome Determinant in Vitiligo

Oripelaye, Mufutau Muphy; Olanrewaju, Fatai Olatunde; Onayemi, O.; Olasode, Olayinka

doi:10.4172/2165-8048.1000242

Cited by 1 publication

(2 citation statements)

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“…While the authors cannot establish a possibility of the wrong diagnosis by the initial clinical assessor, they considered a diagnosis of vitiligo with a possibility of the Koebner phenomenon as the explanation for the extensive facial manifestation. Mufutau et al 7 earlier noted that the Koebner phenomenon, induced by seborrhoeic dermatitis, may be a perpetrating factor in vitiligo, with an attendant challenge in the treatment of the patients.…”

Section: Discussionmentioning

confidence: 99%

“…Vitiligo is a recurring depigmenting condition with a possibility of the development of the Koebner phenomenon in up to one-third of the patients. 7 Koebner phenomenon, which is the presence of new skin lesions at a distant site, has been reported to worsen treatment and prevent recovery in patients. Infections are identified as one of the causes of Koebner phenomenon.…”

Section: B Amentioning

confidence: 99%

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Case Report of Epstein–barr Virus-Induced Autoimmune Vitiligo in Nigeria

Akolawole¹,

Ayosanmi²,

Adeniran³

et al. 2022

EMJ Dermatol

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Vitiligo is an acquired skin depigmenting disorder resulting from melanocytes loss in the epidermis, associated with an autoimmune aetiopathophysiology. However, there are limited data about the association between vitiligo and Epstein–Barr virus (EBV). Hence, the authors present a case of a 43-year-old male who had progressive symmetrical hypopigmented macules, sometimes coalescing to patches that were generalised but predominantly on the face and torso, with scanty involvement of proximal and distal extremities of the body. The diagnosis of vitiligo was made clinically, and seborrhoeic dermatitis was considered as a differential. Since the patient had been offered treatment for seborrhoeic dermatitis using antifungal with no relief and extensive depigmentation, the authors’ working diagnosis was vitiligo and was confirmed with histology. To establish the likely cause of the condition, viral serology for HIV, Cytomegalovirus, herpes, and EBV were completed, but only EBV serology was abnormal. Therefore, the authors report this case to encourage clinicians to consider EBV infection in the aetiology and predisposition for vitiligo to help explore other pathology that the virus may cause.

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Section: Discussionmentioning

confidence: 99%

Section: B Amentioning

confidence: 99%