Seborrheic Keratosis and Verruca, With Special Reference to the Melanotic Variety

Becker, S. William

doi:10.1001/archderm.1951.01570030072009

Cited by 31 publications

(4 citation statements)

References 25 publications

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“…Similar inflammation is found in relation to regressing superficial basal eell eareinoma treated with topical contact sensitizing agents (Helm & Klein 1965). The pathologie proeess observed here is unlike the aeute inflammatory reaction in seborrheie keratoses treated v/ith eroton oil by Mevorah & Mishima (1965) or the abscess with sehorrheic keratosis observed by Becker (1951). We eoneluded that it is possible that seborrheic keratosis may stimulate a delayed hypersensitivity response during its existence.…”

Section: Discussionsupporting

confidence: 73%

“…Freudenthal (1926) and Freudenthal & Spitzer (1933) noted round eell infiltrates with occasional plasma cells with seborrheic keratoses. Becker (1951) men-tioned in his survey of seborrheie keratoses that lymphoeytie inflatnmatioti was present in relation to all his 263 lesions. He noted that the tnore prominent infiltrates contained plasma eells.…”

Section: Discussionmentioning

confidence: 98%

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Inflammatory Seborrheic Keratoses with Mononuclear Cell Infiltration

Berman¹,

Winkelmann²

1978

J Cutan Pathol

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Inflammation in inflammatory seborrheic keratoses was found to be composed of mononuclear cells, particularly lymphocytes. Accumulations of mononuclear cells in the papillary and subpapillary dermis frequently showed no tendency to infiltrate the epithelium. However, dramatic interaction of the seborrheic keratosis and the inflammatory process also was common. The lymphocytic exocytosis into the epithelium followed two basic patterns: eczematous, characterized by intercellular and intracellular edema, microvesicle formation, and epithelial necrosis; and lichenoid, in which a bandlike infiltrate attacked the dermoepidermal junction and hyaline bodies occurred in the infiltrated epithelium and in the dermis. Epithelial changes consisted of necrosis of epithelial cells and related parakeratosis; squamous eddies were occasionally found. Inflammatory cell infiltration in seborrheic keratoses possibly represents a process other than irritation, and we propose that mononuclear cell infiltration in seborrheic keratoses may be related to an involutionary process.

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Section: Discussionsupporting

confidence: 73%

Section: Discussionmentioning

confidence: 98%

Inflammatory Seborrheic Keratoses with Mononuclear Cell Infiltration

Berman¹,

Winkelmann²

1978

J Cutan Pathol

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“…Seborrheic keratoses are subdivided into histologic types such as keratotic and adenoid types [5], serrated, retiform and solid types [2]. In addition to the previously m entioned cellular changes, we have also observed th at the overall histologic type of growth can change to a different one after irritation, as shown in Table VI.…”

Section: (3) Change In Type Of Growth Induced By Experimental Irritationmentioning

confidence: 56%

Cellular Response of Seborrheic Keratosis Following Croton Oil Irritation and Surgical Trauma

Mevorah¹,

Mishima²

1965

Dermatology

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“…showing squamous dysplasia. Becker (1951) has a good discussion of this point. Since the separation of actinic keratosis from S.V., it appears that all the effort of the investigators has been concentrated on the emphasis of this fact and has ignored the occasional dysplastic changes of S.V.…”

Section: Discussionmentioning

confidence: 99%