1990
DOI: 10.1016/0031-9422(90)85221-z
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Seco-germacranolides from Anthemis pseudocotula

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Cited by 18 publications
(5 citation statements)
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“…19 23 Moreover, it is used in Lebanese traditional medicine against abdominal pain, urinary infection and as sedative. 26,27 It is also used for the treatment of cough and cold and as antifungal. 27 The antioxidant activity has been the subject of many researches.…”
Section: Discussionmentioning
confidence: 99%
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“…19 23 Moreover, it is used in Lebanese traditional medicine against abdominal pain, urinary infection and as sedative. 26,27 It is also used for the treatment of cough and cold and as antifungal. 27 The antioxidant activity has been the subject of many researches.…”
Section: Discussionmentioning
confidence: 99%
“…26,27 It is also used for the treatment of cough and cold and as antifungal. 27 The antioxidant activity has been the subject of many researches. 30 In addition, A. tinctoria and A. triumfeti act as defensive agents and exert different biological activities such as anti-inflammation, antiproliferative and inhibitory tumor cell growth.…”
Section: Discussionmentioning
confidence: 99%
“…However, at the outset of our studies the allylation method outlined in Scheme to give such systems containing diverse β-hydroxymethyl substitution 5 had not been examined, aside from the work of Liu and co-workers to additionally γ-substituted adducts involving alkyne-derived molybdenum– or tungsten−π-allyl intermediates ( 4 , M = MoL n or WL n , X = alkyl). , This substitution pattern is present in several sesquiterpene lactones (e.g., Figure ), and the method could be of direct utility in syntheses of anthepseudolide ( 1 ) and the antibacterial hydroxyanthecotulide ( 2 ) and analogues . We also viewed alcohols 5 as potentially versatile substrates for conjugate addition and isomerization chemistry, which could lead to other bioactive natural product classes (see later).…”
mentioning
confidence: 99%
“…In Serbia nine species are known . Three main classes of compounds of chemosystematic interest, such as polyacetylenes, flavonoids, and sesquiterpene lactones, typical for Anthemidae, have been detected in the genus Anthemis . , Among the sesquiterpene lactones, only three types, that is, germacranolides (and seco -germacranolides), eudesmanolides, , and guaianolides, ,,, have been isolated from the genus. The exception is an allergenic lactone with unusual structure (anthecotuloide), the constituent of A. cotula . , Continuing our chemotaxonomic examinations of the Yugoslavian flora belonging to Asteraceae and our search for new compounds of pharmacological interest, we now report the investigation of the aerial parts of Anthemis carpatica Willd, a species usually occurring at elevated, shady and grassy, sandy terrains of the Balkan Penninsula, eastern Alps, and east Carpathian Mountains…”
mentioning
confidence: 99%