Second-Generation 1,550-nm Fractional Photothermolysis for the Treatment of Acne Scars

Chrastil, Brenda; Glaich, Adrienne S.; Goldberg, Leonard Harry; Friedman, Paul M.

doi:10.1111/j.1524-4725.2008.34284.x

Cited by 46 publications

(39 citation statements)

References 21 publications

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“…The percentage of subjects with skin types IV and V included in studies for the treatment of atrophic scarring are very limited compared to lighter skin types due to pigmentation concerns [1][2][3]. Even with the use of hydroquinone pre-and post-treatment, a recently published prospective study of 15 subjects with skin types IV-VI and acne scarring using Erbium-doped YAG laser showed a 50% rate of the PIH [12].…”

Section: Discussionmentioning

confidence: 99%

“…Current methods of treating scarring include traditional fully ablative erbium and carbon dioxide (CO 2 ) treatments as well as non-ablative and ablative fractional resurfacing with CO 2 , erbium:yttrium-aluminum-garnet (Er:YAG), and erbium:yttrium-scandium-galium-garnet (Er:YSGG) lasers [1][2][3][4][5][6][7][8]. These options can be challenging for skin type IV patients and not feasible for patients with skin types V-VI without significant pre-and post-treatment skin conditioning and a hyper-pigmentation risk.…”

mentioning

confidence: 99%

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Retrospective analysis of non‐ablative scar treatment in dark skin types using the sub‐millisecond Nd:YAG 1,064 nm Laser

Badawi

Tome²,

Atteya

et al. 2011

Lasers Surg Med

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Retrospective analysis of non‐ablative scar treatment in dark skin types using the sub‐millisecond Nd:YAG 1,064 nm Laser

Badawi

Tome²,

Atteya

et al. 2011

Lasers Surg Med

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“…Previous experiences with fractional photothermolysis in treating acne scarring have demonstrated its effectiveness [5,6]. In our clinic, we have used fractional photothermolysis with good clinical outcomes in the treatment of acne scars.…”

Section: Introductionmentioning

confidence: 96%

Comparison of a 1,550 nm Erbium:Glass fractional laser and a chemical reconstruction of skin scars (CROSS) method in the treatment of acne scars: A simultaneous split‐face trial

Kim

Kwon

et al. 2009

Lasers Surg Med

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“…In 2 studies investigating the efficacy of EDL in acne scarring with 2 to 6 monthly treatments (82 patients, skin types I-V), 62% to 87% of patients experienced a 51% to 75% scar improvement. 48,49 The average improvement increased proportionally after each treatment and did not significantly differ depending on skin type. 48 More recent studies have confirmed the laser's safety and efficacy in treating acne scarring, even in darker skin types.…”

Section: Acne Scarringmentioning

confidence: 92%

Advances in fractional technology for skin rejuvenation, skin tightening, drug delivery, and treating scars and skin defects

2017

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I n recent decades, there has been a revolution in energy-based treatment options for skin scarring, rejuvenation, and tightening. One of the most promising developments has been the introduction of fractional photothermolysis, developed by Anderson and Manstein in 2004. Fractionated systems deliver laser energy in a grid-like pattern, creating microscopic columns of ablative and/or coagulative damage termed microthermal zones (MTZs), which stimulate collagen remodeling.1 The incorporation of fractional photothermolysis into energy-based devices has allowed less destruction to surrounding tissue, leading to desired results with the minimization of unwanted side effects, leading to both ablative and nonablative laser devices becoming desirable treatment options for cutaneous scarring and rejuvenation. Given their impressive results, newer fractional laser treatment options, including picosecond lasers, quality-switched (QS) lasers, and combined ablative and nonablative lasers, are being investigated for the treatment of these common skin conditions.The following review addresses the current and emerging topics on fractional laser treatment of skin scarring and rejuvenation based on the device type, including ablative, nonablative, QS, picosecond, and hybrid fractional lasers (HFLs). Additionally, newer energy-based fractional devices, such as radiofrequency (RF) with and without microneedling and the use of fractionated technology for drug delivery, are discussed in the context of these common skin conditions. Fractionated lasersTreatment options for cutaneous scars and skin rejuvenation have evolved significantly since the rise in popularity of ablative lasers in the 1990s. Newer treatment options, including ablative fractional lasers (AFL) and nonablative fractional lasers (NAFL), have garnered favor, given the milder side effect profile in comparison with traditional fully ablative lasers. Ablative fractional lasersAcne scarring AFLs were developed in an attempt to achieve the efficacy of traditional ablative lasers with the milder side effect profile of fractional technology. Although a single treatment produces less dramatic, albeit noticeable, results than traditional fully ablative lasers can, multiple treatments result in greater clinical improvement.2 Currently, there are 3 types of AFLs available for scar treatment: the 10600-nm carbon dioxide (CO2), the 2940-nm erbium:yttrium aluminum garnet (Er:YAG), and the 2740-nm yttrium scandium gallium garnet (YSGG) lasers. AFL is associated with the increased risk of both protracted erythema and postinflammatory hyperpigmentation (PIH) in darker skin types, which has led many clinicians to prefer a longer series of NAFL treatments over AFL treatments to achieve similar results with a lower risk of side effects.Multiple studies support the efficacy of the fractional CO2 laser in acne scars. The overwhelming majority of these studies investigate the utility of these lasers in atrophic facial scars. While NAFLs typically require multiple sessions to achieve modest ...

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Second-Generation 1,550-nm Fractional Photothermolysis for the Treatment of Acne Scars

Abstract: Fractional photothermolysis is a safe and efficacious treatment modality for the treatment of all types of acne scars of all severities. No adverse effects were noted, including in patients with Fitzpatrick Skin Types III to V.

Cited by 46 publications

References 21 publications

Retrospective analysis of non‐ablative scar treatment in dark skin types using the sub‐millisecond Nd:YAG 1,064 nm Laser

Retrospective analysis of non‐ablative scar treatment in dark skin types using the sub‐millisecond Nd:YAG 1,064 nm Laser

Comparison of a 1,550 nm Erbium:Glass fractional laser and a chemical reconstruction of skin scars (CROSS) method in the treatment of acne scars: A simultaneous split‐face trial

Advances in fractional technology for skin rejuvenation, skin tightening, drug delivery, and treating scars and skin defects

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