Second-intention healing of exposed facial-scalp bone after Mohs surgery for skin cancer: Review of ninety-one cases

Snow, Stephen N.; Stiff, Mark A.; Bullen, Ricardo; Mohs, Frederic E.; Chao, Wei-Hsiung

doi:10.1016/s0190-9622(94)70209-8

Cited by 70 publications

(72 citation statements)

References 18 publications

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“…Thus the ablation of the outer table of the skull by perforation or milling gives access to these diploic veins which can directly feed an immediate skin graft on one hand [6]; and on the other hand constitutes a tissue wound in which will trigger the repair process conducting to the formation of granulation tissue [13] external table leads the cell differentiation towards the formation of granulation tissue. This technic requires regular dressing changes to maintain a moist environment [7] [19]. All kind of dressing may be used if only are they occlusive.…”

Section: Discussionmentioning

confidence: 99%

Technique of Granulation Tissue Genesis from Diploe

Kpelao¹,

Moumouni²,

Anthony³

et al. 2018

MPS

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Section: Discussionmentioning

confidence: 99%

Technique of Granulation Tissue Genesis from Diploe

Kpelao¹,

Moumouni²,

Anthony³

et al. 2018

MPS

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“…The healing time of the skull wounds, ranging between 66 and 85 d, showed a proliferation rate of 0.07 cm d −1 . In human medicine, the treatment of scalp wounds with exposed bone is very challenging, particularly when the periosteum is exposed (Snow et al 1994. In a retrospective study, the plant-derived dressing 1 Primary Wound Dressing ® was an effective therapy for the treatment of scalp wounds with exposed bone.…”

Section: Discussionmentioning

confidence: 99%

Management of severe head injury with brain exposure in three loggerhead sea turtles Caretta caretta

Franchini¹,

Cavaliere²,

Valastro³

et al. 2016

Dis. Aquat. Org.

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The loggerhead Caretta caretta is the most common sea turtle in the Mediterranean. Currently, sea turtles are considered endangered, mainly due to the impact of human activities. Among traumatic lesions, those involving the skull, if complicated by brain exposure, are often life-threatening. In these cases, death could be the outcome of direct trauma of the cerebral tissue or of secondary meningoencephalitis. This uncontrolled study aims to evaluate the use of a plantderived dressing (1 Primary Wound Dressing ® ) in 3 sea turtles with severe lesions of the skull exposing the brain. Following surgical curettage, the treatment protocol involved exclusive use of the plant-derived dressing applied on the wound surface as the primary dressing, daily for the first month and then every other day until the end of treatment. The wound and peri-wound skin were covered with a simple secondary dressing without any active compound (non-woven gauze with petroleum jelly). Data presented herein show an excellent healing process in all 3 cases and no side effects due to contact of the medication with the cerebral tissue.

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“…In the treatment of scalp wounds, exposure of the calvarian bone presents particular challenges [6]. Speedy closure with a flap and/or skin graft is commonly considered the preferred treatment [10], although this may involve problems arising from donor site mobility, duration of the surgical procedure, and later on absence of hair regrowth, especially in free flap reconstruction.…”

Section: Discussionmentioning

confidence: 99%

“…38 cases, and Snow et al [6] assessed a very low rate of soft tissue infection (2.7%) in 115 cases. The patients' responses to the telephone survey indicated satisfaction with the cosmetic results.…”

Section: Disclosure Statementmentioning

confidence: 99%

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A Plant-Derived Wound Therapeutic for Cost-Effective Treatment of Post-Surgical Scalp Wounds with Exposed Bone

et al. 2014

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Background: To evaluate efficacy and cost-effectiveness of a plant-derived wound dressing (ONE), a mixture of hypericum oil (Hypericum perforatum L.) and neem oil (Azadirachta indica A. Juss.), in scalp wounds with exposed bone. Patients and Methods: All patients with scalp wounds with exposed bone, following the excision of skin tumors, and treated with ONE in 2011 were included. Time of healing, wound size, area of exposed bone, ease of handling, pain, and complications were evaluated. Costs of dressings and nursing time were compared with those cited in literature for other treatment modalities. Results: Fifteen consecutive patients with a mean age of 76.87 ± 10.3 years (59-90 years) were analyzed. The mean wound size was 10.9 ± 6.84 cm² (0.4-22.6 cm²) with 4.8 ± 5.9 cm² (0.3-20.7 cm²) of exposed bone. The time of complete healing by secondary intention was 8.1 (4-20) weeks. Rapid formation of granulation tissue was observed which after 4 weeks covered the entire exposed bone surface in 11 of 15 cases (73%). Dressing change was simple with no pain reported; no infections or other complications occurred. Using ONE for a mean healing time of 56.7 days resulted in mean costs of EUR 423.73, which is substantially lower than those published for fascia lata, negative pressure therapy, or collagen matrix followed by skin grafting (EUR 1,612.82, EUR 4,411.80 and EUR 1,503.72, respectively). Conclusion: This retrospective, non-controlled analysis supports ONE as a simple-to-use and safe treatment option for scalp wounds with exposed bone. Treatment costs compare favorably to those published for other treatment modalities.

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Second-intention healing of exposed facial-scalp bone after Mohs surgery for skin cancer: Review of ninety-one cases

Cited by 70 publications

References 18 publications

Technique of Granulation Tissue Genesis from Diploe

Technique of Granulation Tissue Genesis from Diploe

Management of severe head injury with brain exposure in three loggerhead sea turtles Caretta caretta

A Plant-Derived Wound Therapeutic for Cost-Effective Treatment of Post-Surgical Scalp Wounds with Exposed Bone

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