Second-order advantage applied to simultaneous spectrofluorimetric determination of paracetamol and mefenamic acid in urine samples

Electrochemical Determination of Paracetamol Using Fe3O4/Reduced Graphene-Oxide-Based Electrode

“…Numerous methods have been employed for detecting PRC, alone and in mixtures, in biological samples and formulations, such as HPLC (high-performance liquid chromatography) [4,5], liquid chromatography-mass spectrometry (LC-MS) [2,6,7], spectrofluorimetry [8], electrochemical techniques [9,10], chemiluminescence [11,12]. However, these methods suffer from several disadvantages such as being time-consuming, high cost, and a requirement for sample pretreatment.…”

A high effect polymer-free covalent layer by layer self-assemble carboxylated MWCNTs films modified GCE for the detection of paracetamol

“…The GCE used as the substrate A c c e p t e d M a n u s c r i p t 6 hour, and then kept in ethylenediamine for 1h, at last dropped 5μL 1 mg mL -1 activated CMWCNTs on the GCE surface and dry in air. Recycle the above LBL assembly procedure can obtained the (CMWCNTs-NHCH 2 CH 2 NH) n /GCE.…”

“…Thus, a simple, fast, sensitive, and accurate analytical method for determining paracetamol in pharmaceutical preparations and human plasma is needed. A variety of methods have been used for determining paracetamol in pharmaceutical tablets and biological fluids, e.g., spectrophotometry [1], titrimetry [2], liquid chromatography [3], chemiluminescence [4], capillary electrophoresis [5], spectrofluorimetry [6], thin layer chromatography [7], micellar electrokinetic chromatography [8], and electrochemical techniques [9,10].…”

A Glassy Carbon Electrode Modified with Multiwalled Carbon Nanotube/Chitosan Composite as a New Sensor for Simultaneous Determination of Acetaminophen and Mefenamic Acid in Pharmaceutical Preparations and Biological Samples

“…Accordingly determination of the levels of these present in pharmaceuticals is of considerable importance, to prevent overdoses leading to toxic effects. Most of the proposed methods for the simultaneous determination of these compounds are based on UV-VIS spectrophotometry [37,38], NMR [39] and HPLC [40] techniques. However, in spectrophotometry method the absorption peaks of ACT and MEF overlap.…”