2014
DOI: 10.1155/2014/287479
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Secondary Hemophagocytic Syndrome Associated with Richter’s Transformation in Chronic Lymphocytic Leukemia

Abstract: Hemophagocytic syndrome (HPS) is an extremely rare condition arising from the overactivation of one's own immune system. It results in excessive inflammation and tissue destruction. Prompt initiation of treatment is warranted in either scenario in order to decrease mortality. Most cases are triggered by infectious agents, malignancy, or drugs. We describe the first case of a CLL patient presenting with HPS due to acquisition of EBV-related large cell lymphoma in the setting of profound immunodeficiency.

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“… Hospital-acquired bacterial infection leading to potential sepsis, although blood and urine cultures subsequently turned out negative 11 .  Hemophagocytic syndrome associated with CLL 12 .…”
Section: Secondary Clinical Criteriamentioning
confidence: 99%
“… Hospital-acquired bacterial infection leading to potential sepsis, although blood and urine cultures subsequently turned out negative 11 .  Hemophagocytic syndrome associated with CLL 12 .…”
Section: Secondary Clinical Criteriamentioning
confidence: 99%