In the middle of April 2021, the infection rate due to 2<sup>nd</sup> wave of COVID-19 attained a peak alarming level. Total COVID-19 hospital accommodation became inadequate with respect to the demand of COVID-19 patients. Several unused schools, community halls and auditoriums were converted to safe-homes for COVID-19 patients and home isolated accommodations. Two local clubs at Salt Lake, Sector 4, Kolkata was collaborated to run a COVID-19 Safe-home at Basanti Devi Vidyapith, Basanti Devi colony, at the beginning of May 2021. On behalf of the coordinators, a few Electro-Homeopathy (EH) practitioners were voluntarily engaged themselves to look after the patients. A complete report on the successful management of COVID-19 patients using Electro-Homeopathy treatment has been presented here in details. The efficacy of Electro-Homeopathy for COVID-19 treatment and in-depth details of the philosophy of EH along with EH treatment methodology has been discussed.