Secondary metabolites from
            <i>Valeriana jatamansi</i>
            with their anti-inflammatory activity

Trâm, Lê Huyền; Thong, Nguyen Van; Thủy, Lê Thị Thanh; Anh, Nguyễn Tuấn; Minh, Nguyen Hoang; Minh, Trần Thị; Phuong, Nguyen Thi Hong; Ha, Tran Thu; Nguyen, Thi Minh Nguyet; Le, Duc Dat; Hiep, Nguyen Dinh; Park, Jong-Tae; Chinh, Truong Thi To; Hương, Trần Thu; Lee, Mina

doi:10.1080/14786419.2021.2004600

Cited by 4 publications

(2 citation statements)

References 32 publications

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“…Anti‐inflammatory assay was conducted following our previous report [29] . Particularly, cell viability was calculated due to the percentage cell survival in a dose‐dependent manner between treated and untreated samples.…”

Section: Methodsmentioning

confidence: 99%

“…Anti-inflammatory assay was conducted following our previous report. [29] Particularly, cell viability was calculated due to the percentage cell survival in a dose-dependent manner between treated and untreated samples. Briefly, RAW267.4 cells were maintained in DMEM complete culture medium with 10 % FBS and 100 U pen/strep at 37 °C in 5 % incubator through 4-5 passages.…”

Section: Cell Viability Of Anti-inflammatory Assaymentioning

confidence: 99%

See 1 more Smart Citation

New Dibenzocyclooctadiene Lignans and Phenolics from Kadsura heteroclite with Anti‐Inflammatory Activity

Thuy,

Tram,

Anh

et al. 2023

Chemistry & Biodiversity

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A chemical investigation of K. heteroclite led to isolation of two new dibenzocyclooctadienes (1 and 2) together with 14 known compounds (3‐16) by using multiple chromatographic techniques. New compounds (1 and 2) were obtained and identified by spectroscopic methods (HRESIMS, 1D and 2D NMR, and ECD) as well as by comparison of their experimental data with those reported in the literatures. All the isolates were evaluated for their ability to modulate TNF‐α production in lipopolysaccharide (LPS) stimulated RAW264.7 cells. Among them, compound 5 displayed the most inhibition against tumor necrosis factor (TNF)‐α production with IC50 value of 6.16±0.14 µM. Whereas, compounds (1, 3, and 6) showed the significant inhibition (IC50 values ranging from 9.41 to 14.54 µM), and compounds (2, 4, 9, 10, 13, 15, and 16) exhibited moderate inhibition (IC50 values ranging from 19.27 to 40.64 µM) toward TNF‐α production, respectively.

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Section: Methodsmentioning

confidence: 99%

Section: Cell Viability Of Anti-inflammatory Assaymentioning

confidence: 99%