Secondary Metabolites from the Twigs of Cinnamomum camphora

Wu, Lei; Xiong, Wei; Hu, Juwu; Wu, Jing; Zi-jiang, LI; Gao, Yangfei; Liu, Dan; Liu, Ying; Liu, Wei; Liang, Min; Si, Chuanling; Bae, Young-Soo

doi:10.1007/s10600-019-02686-8

Cited by 13 publications

(2 citation statements)

References 16 publications

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“…Apart from analgesic, Kafūr has also been reported for many other pharmacological activities might be due to the presence of monoterpenes, phenolic derivatives, flavonoids, lignans, sterols, and terpenoids [34,37,39,40,[43][44][45]46]; which are reported to have antinociceptive/analgesic [49,50], antioxidant [52], antimicrobial [53][54][55][56][57] and wound healing properties [64]. The antibacterial activity was achieved by different mechanisms like partial degradation of the cell membrane, increased membrane permeability, cytoplasm leakage, noticeable distortion, shrinkage of bacterial cells, and membrane protein structural changes [56].…”

Section: Discussionmentioning

confidence: 99%

Kafur (C. Camphora L.)–an Updated Review of Its Ethnopharmacology, Phytochemistry and Pharmacology

Usmani

Jahan²,

SOFIYA³

2022

Int J Pharm Pharm Sci

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The objective of present review was to provide comprehensive information on Cinnamomum camphora L. on its ethnomedicinal uses, phytochemical, and pharmacological activities and provide insights into potential opportunities for future research. A thorough literature search was done to gather all the available updates on Kafūr for its mizāj (temperament), medicinal properties, and traditional uses. Classical Unani books and books on ethnomedicine and ethnobotany in English were referred for literature review. The information on phytochemical and pharmacological activities of C. camphora was collected from PubMed, Science Direct, Google Scholar, and Research Gate using keywords C. camphora, Kafūr, kapur, and camphor. The species name was checked with www. theplantlist. org. The material published in Urdu, Persian, Arabic, and English was included in the review. C. camphora is used as an analgesic and antiseptic in Unani and other traditional systems of medicine for a long. It possesses various bioactive compounds viz. terpenoids, flavonoids, glycosides, coumarins, fatty acids, lignans, alkaloids, etc. Out of all these, camphor is one of the volatile compounds which has many pharmacological activities including anti-nociceptive, anti-oxidant, anti-bacterial, anti-microbial, wound healing, and hepatoprotective.

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Section: Discussionmentioning

confidence: 99%

Kafur (C. Camphora L.)–an Updated Review of Its Ethnopharmacology, Phytochemistry and Pharmacology

Usmani

Jahan²,

SOFIYA³

2022

Int J Pharm Pharm Sci

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“…The Cinnamomum camphora is known as an evergreen tree of Lauraceae, widely distributed in China and Japan [ 1 ]. The C. camphora is not only a high-quality resource of wood but also plays an important role in the utilization of fragrance, medicine, and chemical industry due to its special aromatic and medicinal value [ 1 , 2 , 3 , 4 ]. In addition, some studies indicated that the extract of C. camphora leaf and its bioactive components have antioxidant, anti-inflammatory, antialgal, antimicrobial, and insecticidal activities in vitro, as well as the effects of an anticonvulsant, neuroprotective, and alleviating atopic dermatitis in vivo [ 2 , 5 , 6 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

Optimization and Characterization of Microwave-Assisted Hydro-Distillation Extraction of Essential Oils from Cinnamomum camphora Leaf and Recovery of Polyphenols from Extract Fluid

et al. 2020

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In this study, the efficiency of microwave-assisted hydro-distillation (MAHD) to extract essential oil from Cinnamomum camphora leaf, and the recovery of polyphenols from extract fluid were investigated. The effects of microwave power, liquid-to-material ratio, and extraction time on the extraction efficiency were studied by a single factor test as well as the response surface methodology (RSM) based on the central composite design method. The optimal extraction conditions were a microwave power of 786.27 W, liquid-to-material ratio of 7.47:1 mL/g, and extraction time of 35.57 min. The yield of essential oil was 3.26 ± 0.05% (w/w), and the recovery of polyphenols was 4.97 ± 0.02 mg gallic acid equivalent/g dry weight under the optimal conditions. Furthermore, the comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry (GC×GC-TOFMS) was used to characterize the essential oils of fresh and fallen leaves, and 159 individual compounds were tentatively identified, accounting for more than 89.68 and 87.88% of the total contents, respectively. The main ingredients include sabinene, l-β-pinene, β-myrcene, α-terpineol, 3-heptanone, and β-thujene, as well as δ-terpineol and 3-heptanone, which were first identified in C. camphora essential oil. In conclusion, the MAHD method could extract essential oil from C. camphora with high efficiency, and the polyphenols could be obtained from the extract fluid at the same time, improving the utilization of C. camphora leaf.

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