Secondary nonmonosymptomatic enuresis diurna as the first manifestation of transitional cell papillary carcinoma of the bladder in a 14-year-old girl

Abstract

A 14-year-old girl presented with secondary nonmonosymptomatic enuresis diurna and urge incontinence. The patient had no history of medical, psychological or behavioral problems. Systemic physical and neurological examinations and laboratory investigations revealed no abnormality. An ultrasound showed an intravesical tumor that was subsequently excised. Histopathology revealed transitional cell papillary bladder carcinoma of low-grade malignancy. All previously reported cases have presented with the symptoms of gross hematuria or urinary tract infection. To our knowledge, this case represents the first childhood case of transitional cell carcinoma of the bladder presenting with secondary nonmonosymptomatic enuresis diurna and urge incontinence. Additionally, our experience with the above case suggests that the investigation of secondary enuresis symptoms should be thorough and include a cystoscopic examination.