Secondary Pancreatic Involvement of Mycosis fungoides Detected by a Clinically Palpable Mass

Abstract

A patient with a 4-year history of mycosis fungoides, who presented a pancreatic spreading of the disease, detected by a clinically palpable mass, is reported and discussed with a review of the literature. Mycosis fungoides (MF) is a T cell lymphoma primarily localized to the skin. Laparoscopic staging and autopsy studies, however, have shown that lymph node involvement or visceral spreading is common in the course of the disease [1–3]. Among visceral manifestations of MF, pancreas infiltration is found in 20–40% of autopsied cases [1, 2, 4]. Occurrence of a palpable pancreatic mass has never been described. We report a patient with a long-standing MF, and a secondary pancreatic extension detected by a palpable mass.

Autopsy case of CD4–/CD8– cutaneous T‐cell lymphoma presenting disseminated pagetoid reticulosis with aggressive granulomatous invasion to the lungs and pancreas

“…Kaplanski et al . described a case of MF with secondary involvement of the pancreas without lymphadenopathy or invasion of the liver or spleen 18 . These were all diagnosed as cases of MF, showing the typical morphological and immunochemical features.…”