This article reviews the application of high pressure gas xenon (HPXe) time projection chambers to neutrinoless double beta decay experiments. First, the fundamentals of the technology and the historical development of the field are discussed. Then, the state of the art is presented, including the prospects for the next generation of experiments with masses in the ton scale. So far, HPXe detectors have operated at ambient temperature with pressures varying between 5 bar -St.Gotthard TPC [Iqbal et al., 1987]-and 20 bar -NEXT-DBDM prototype [Álvarez et al., 2012a]-. The NEXT-White detector [Monrabal et al ., 2018] is currently taking data at 10 bar. In practice, at standard temperature, the operational pressure for ton-scale detectors will be in the range 10 bar to 20 bar. Given the density of xenon gas at a pressure of 1 bar and 300 K temperature (5.761 kg m −3 ), a HPXe TPC of 10 m 3 operating at 10 bar would hold a target mass of near 600 kg ( 1.2 ton at 20 bar). The detector dimensions, while large (e.g. 3.2 m length by 3 m diameter) appear as technically feasible. On the other hand, the NEXT demonstrators (NEXT-DEMO, NEXT-DBDM and NEXT-White) have shown excellent energy resolution and a powerful topological signature in this pressure range.However, pressure can be traded with temperature, as illustrated in figure 1, which shows the four isochoric (constant density) curves corresponding to pressures of 5, 10, 15 and 20 bar (at a temperature of 20 • C). An interesting possibility would be cooling the detector to temperatures near the liquefaction Frontiers