Development of electronic learning (E-learnings), learning resources are teaching materials and a variety of information developed and packaged in various forms based on information and communication technology and used in the learning process. For this reason, special techniques for subject design, techniques are needed. specific learning, special methodologies through various media, and special organizational and organizational arrangements. In multimedia learning, the design process requires design methods, development tools, inspection models and skills in Information Technology systems. It is necessary to formulate a Holistic Method which considers all related aspects in order to guide the quality of good design in designing Multimedia Learning. Implementing the findings of the Holistic Method formulation to build multimedia learning with good design quality. This study formulates the stages of multimedia development which include: Creative Brief, Design, Material Preparation, Scripting, Testing, Distribution. The multimedia software development process will be guided by 15 guiding elements which are grouped into 5 elements.