Secondary visual loss due to inhalation and cutaneous poisoning by methanol and toluene. Presentation of a clinical case

Toxic optic neuropathy due to methanol: About two cases

“…It is a serious poisoning that generally requires hospitalization in intensive care. Despite current treatments, mortality rates are between 26% and 50%, and survivors are generally subject to neurological and visual aftereffects [8]. According to studies, the prevalence of long-term visual sequelae of toxic optic neuropathy caused by exposure to methanol is 40% [9][10].…”

“…Ethanol is administered by infusion to achieve blood ethanol levels of approximately 150 mg/dL. To date, there is no evidence of the effectiveness of intravenous corticosteroids; however, cases of improvement in visual function with the use of prednisone at doses of 1 mg/kg/day for one month and vitamin B1 intramuscularly at 100 mg/day have been described [8]. Both patients presented to the emergency room within two days and did not receive antidotal treatment.…”