Secretory Carcinoma of the Skin

Requena, Luís; Sangüeza, Omar P.

doi:10.1007/978-3-319-45704-8_31

Cited by 1 publication

(6 citation statements)

References 7 publications

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“…Due to the long-term potential to recur and metastasize, regular follow-up and examination of the patient are recommended [ 19 , 80 , 92 ]. Only a few adnexal malignancies show a favorable prognosis, and no cases of recurrent or metastatic disease were reported [ 183 , 189 , 193 , 195 ].…”

Section: Discussionmentioning

confidence: 99%

“…Grossly, MASC presents a solitary, well-circumscribed, but unencapsulated tumor with a variable cystic component. Cutaneous SCA frequently involves the axilla, followed by head and neck, flank, and forearm [ 183 ]. The size usually ranges from 0.4 to 6 cm [ 183 ].…”

Section: Tumors With Apocrine and Eccrine Differentiationmentioning

confidence: 99%

“…Cells are frequently negative for basal/myoepithelial markers, with variable expression of calponin and p63 [ 176 ]. Positive staining with EGFR, EMA, MUC1 (mucin 1), MUC4 (mucin 4), SOX10 (SRY-Box Transcription Factor 10), and GCDFP-15, among others, have also been reported, although their expression is variable and non-specific [ 175 , 183 ].…”

Section: Tumors With Apocrine and Eccrine Differentiationmentioning

confidence: 99%

“…The sentinel lymph node mapping is not indicated in primary cutaneous secretory carcinoma [ 184 ]. No recurrent or metastatic disease cases have been reported yet, and the prognosis is good after complete excision ( Table 2 ) [ 183 ].…”

Section: Tumors With Apocrine and Eccrine Differentiationmentioning

confidence: 99%

“…Cutaneous SCA frequently involves the axilla, followed by head and neck, flank, and forearm [183]. The size usually ranges from 0.4 to 6 cm [183].…”

Section: Secretory Carcinomamentioning

confidence: 99%

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Current Diagnosis and Treatment Options for Cutaneous Adnexal Neoplasms with Apocrine and Eccrine Differentiation

Płachta

Kleibert

Czarnecka

et al. 2021

IJMS

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Adnexal tumors of the skin are a rare group of benign and malignant neoplasms that exhibit morphological differentiation toward one or more of the adnexal epithelium types present in normal skin. Tumors deriving from apocrine or eccrine glands are highly heterogeneous and represent various histological entities. Macroscopic and dermatoscopic features of these tumors are unspecific; therefore, a specialized pathological examination is required to correctly diagnose patients. Limited treatment guidelines of adnexal tumor cases are available; thus, therapy is still challenging. Patients should be referred to high-volume skin cancer centers to receive an appropriate multidisciplinary treatment, affecting their outcome. The purpose of this review is to summarize currently available data on pathogenesis, diagnosis, and treatment approach for apocrine and eccrine tumors.

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Section: Discussionmentioning

confidence: 99%

Section: Tumors With Apocrine and Eccrine Differentiationmentioning

confidence: 99%

Section: Tumors With Apocrine and Eccrine Differentiationmentioning

confidence: 99%

Section: Tumors With Apocrine and Eccrine Differentiationmentioning

confidence: 99%

“…Cutaneous SCA frequently involves the axilla, followed by head and neck, flank, and forearm [183]. The size usually ranges from 0.4 to 6 cm [183].…”

Section: Secretory Carcinomamentioning

confidence: 99%

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