Secretory defense system (SDS) in health and disease

Abstract

S 381and WI-38 cells was determined in a group of 8 seropositive adults with no history of clinical measles. The results showed that lymphocytes from the adults with measles effected as much as a 13% increase in Cr B1 release from WI-M1 as compared to WI-38 cells. The lymphocytes from the two individuals with negative histories showed a much diminished release. These results indicate that the measurement of lymphocytotoxic response may be a useful in vitro method for studying delayed hypersensitivity to measles virus.Absence of serum immunoglobulin E in newborns: Heterogeneity in time of synthesis in infants. MICHAEL BAZARAL, H.

The Immunity of the Human Foetus and Newborn Infant

“…Comparison of individual pairs of sera (mother and child) showed no direct relationship between the two concentrations. By contrast to the raised lysozyme level in the serum of newborn infants, Stiehm et al (1971) found less of this enzyme in their tears (0.62 mg/ml) than in the tears of adults (2 mg/ml). Adinolfi ( 1972) arrived at similar conclusions and extended information on lysozyme activity in newborn infants by further aspects.…”

“…Miller ( 1969bMiller ( , 1971) published very important studies elucidating the character of the neonatal migratory activity deficiency of neonatalleucocytes. It was not until the in vitro techniques described above were evolved, however, that the migratory activity of neonatal leucocytes in vitro could be characterized exactly.…”

“…19 REDUCED Miller 1971Klein et al 1976Miler et al 1979aTono-Oka et al 1979Pahwa et al 1977Maroni 1974Miler et al 1979aMease et al 1980Hahn et al 1976Miller 1975Miller 1971Maroni 1974REDUCED Kretschmer et al 1976Weston et al 1977Klein et al 1976Arenson et al 1978NORMAL OR Pahwa et al 1977 Chemotaxis in vivo: Persistent neutrophilia, mononuclear phase of cellular infiltrate in skin (Rebuck's skin window) delayed and reduced Eitzman, Smith 1959Sheldon, Caldwell 1963Prindull 1968Bullock et al 1969 Phagogytosisbactericidal activity Phagocytosis in whole blood REDUCED Tunicliffe 1910Bracco 1948Matoth 1952Criscione 1955 Xanthou et al 1975Kretschmer et al 1976Wehinger, Hofacker 1976Orlowski et al 1976Weston et al 1976Klein et al 1976Oseas, Lehrer 1978Shigeoka et al 1979REDUCED Matoth 1952(with inade-Edwards et al 1958 We conclude this chapter with a comprehensive survey of all the mam immune reactions of the newborn infant hitherto described (Tab.…”