This study aimed to determine whether autochthonous high-intensity D. repens micro laremia leads to haematological changes in companion dogs. Dogs with hypermicro laremia presented to the District Veterinary Centre, Kannur were selected for the study. A total of one hundred animals were positive for hypermicro lariaemia with D. repens based on peripheral blood smear examination and Knott's test. Of these, three dogs were concurrently positive for sheathed micro laria (MF) of Brugia spp. Interestingly, an adult live worm of D. repens approximately eight cm in length was detected on a subcutaneous mass on the hind limb of a hypermicro laremic animal in the study. We compared the hematological parameters of 100 autochthonous hypermicro laremic dogs and 15 uninfected dogs. The hematological ndings in the study are nonregenerative mild to moderate anemia, moderate to severe thrombocytopenia, leucocytosis with granulocytosis, lymphocytosis and monocytosis in comparison to the uninfected group of dogs. The pathogenicity of naturally occurring hypermicro laremia is poorly studied, and knowledge of its epidemiology, host-parasite relationship and impact on various organs is warranted for better prevention and control, especially in hot-spot areas.