Secular trends of hip fractures in France: impact of changing characteristics of the background population

Garofoli, Romain; Maravic, Milka; Ostertag, Agnès; Cohen‐Solal, Martine

doi:10.1007/s00198-018-4666-7

Cited by 21 publications

(15 citation statements)

References 31 publications

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“…This significant increase in the HF incidence rate in Romanian women in the last decade is rare for an European country, as most published data from western and northern countries observed decreasing or stable trends. In France, decreasing trends were found both in crude incidence rates and especially age- standardized rates despite the increased global number of HF throughout a 12-year period (11). Recent data from Poland showed an increasing trend in the total number of HF and incidence rates, in both women and men (12,13).…”

Section: Discussionmentioning

confidence: 97%

Incidence and Time Trend of Hip Fractures in Romania: a Nationwide Study From 2008 to 2018

et al. 2019

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Background. Hip fractures are a major issue of public health as they are responsible for high morbidity, excess mortality and costs. There are differences in Europe and worldwide in the incidence rates of hip fractures and time trends, in the context of the population aging. Ten years ago, we characterized the incidence of hip fracture in Romania using data from the national hospital discharge register. Objective. This is the first Romanian study to assess the hip fracture incidence rates over a period of 11 years, between 2008 and 2018. Subjects and Methods. This analysis is a nationwide retrospective study on hospitals reporting primary DRG data on hip fracture, using a rigorous definition with both diagnostic and surgical procedure codes. The population aged 40+ was stratified in 5-year intervals and both the crude incidence rates and the adjusted incidence rates of hip fracture using standardization on age for the 2018 reference population were calculated in women and men. Results. From 2008 to 2018, the number of hip fractures rose by 53 % in women (from 7513 to 11512) and 22.4 % in men (from 4266 to 5220). Meanwhile, the Romanian population over 40 years increased by 12.5% in women and 14.2% in men. The crude incidence rate rose by 36.2% in women and 7.2% in men and the age-standardized incidence rates by 27.4% in women and 6% in men. These increases are mostly based on 85+ age populations' changes. Conclusions. In Romania, the hip fractures incidence continues to grow throughout an 11-year-period, especially in women, representing an increasing burden for our society.

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Section: Discussionmentioning

confidence: 97%

Incidence and Time Trend of Hip Fractures in Romania: a Nationwide Study From 2008 to 2018

et al. 2019

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“…suggested that hip fracture rates may be increasing in Poland [3], France [4], Japan [5], Italy [6], and China [7].…”

Section: Introductionmentioning

confidence: 99%

“…A recent meta-analysis showed that the one year mortality rate was 13.96% after hip fracture in mainland China [ 1 ], and hip fracture was associated with excess short- and long-term all-cause mortality in Europe and USA [ 2 ]. At the same time, hip fracture incidence data suggested that hip fracture rates may be increasing in Poland [ 3 ], France [ 4 ], Japan [ 5 ], Italy [ 6 ], and China [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

High platelet-to-lymphocyte ratio predicts poor survival of elderly patients with hip fracture

Wang¹,

Wang²,

Yang³

et al. 2020

International Orthopaedics (SICOT)

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Purpose The platelet-to-lymphocyte ratio (PLR) has been extensively studied in various diseases. However, the relationship between PLR and hip fracture remains unknown. The aim of this study was to evaluate whether PLR would be an independent prognostic factor in elderly hip fracture patients. Methods Between January 2014 and December 2018, a retrospective cohort study was conducted in a orthopaedic centre, China. A total of 460 hip fracture patients were included. PLR was calculated as the ratio of platelet to lymphocyte counts and divided into high PLR group (≥ 189) and low PLR group (< 189) by using the receiver operating characteristic (ROC) curve. The relationship between PLR and one year all-cause mortality rate was assessed by univariate and multivariate Cox proportional hazard models. Further subgroup analysis stratified by different clinical and biological characteristics was performed to make the results more accurate. Results After a median follow-up of 32.0 months (range, 12.0-75.4), 92 patients (mortality rate: 20.0%) died within one year. PLR was significantly higher in dead patients compared with alive patients (p < 0.05), and high PLR group also had a high mortality rate (32.21% vs. 14.15%, p < 0.001). After multivariate adjustment, high PLR remained an independent predictor for one year all-cause mortality (adjusted hazard ratio (HR) 1.56, 95% confidence interval (CI) 1.02-2.41, p = 0.041). Moreover, advanced age (HR 1.05, 95% CI 1.01-1.08), male (HR 1.62, 95% CI 1.06-2.45), CCI ≥ 2 (HR 2.83, 95% CI 1.64-4.89), conservative treatment (HR 5.94, 95% CI 3.71-9.73), low haemoglobin level (HR 1.02, 95% CI 1.01-1.04), and low albumin level (HR 1.07, 95% CI 1.02-1.13) were independent risk factors for survival. Furthermore, subgroup analysis results were consistent with the main findings in most stratified groups. Conclusion This study highlights that high PLR (≥ 189) is associated with increased one year all-cause mortality in elderly hip fracture patients. As PLR is a simple indicator that can be calculated from the blood routine test, it can be easily performed in usual clinical practice.

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“…In a study conducted in France from 2002 to 2013, the incidence of hip fracture rose by 4.8% in women (from 49,287 to 51,661) and 21.8% in men (from 12,716 to 15,482) aged over 59 years. Meanwhile, the French population over 59 years increased, with a rise of 21.3% in women and 28.7% in men, resulting in a decrease in the crude incidence rates of 13.6% in women and 5.4% in men [35]. In a similar study in the USA using 2002 to 2015 Medicare data, authors reported that for women ≥ 65 years old, age-standardised hip fracture rates declined each year from 2002 (844/100,000) to 2012 (741/100,000) and then plateaued in 2013 (741/ 100,000) [36].…”

Section: Changing Trends Of Hip Fracture and Its Researchmentioning

confidence: 99%

Depicting developing trend and core knowledge of hip fracture research: a bibliometric and visualised analysis

et al. 2021

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Background Hip fracture is common and carries high morbidity and mortality; thus, it has become a vital concern. We aim to analyse the present status, worldwide trends in hip fracture and state of clinical research. Methods Publications from 2000 to 2019 were retrieved from the Web of Science database and analysed using a bibliometric methodology. VOSviewer software was utilised for analysis. Results In total, 6139 publications were included, and publications increased annually from 152 in 2000 to 592 in 2019. U.S. researchers have produced the most publications, the highest H-index and the greatest number of citations. Osteoporosis International has published the most papers on the topic. Leading researchers, contributing institutions, their cooperative relationships and scientific masterpieces have been identified. The publications can be divided into five clusters: ‘mortality’, ‘surgical management’, ‘rehabilitation’, ‘osteoporosis’ and ‘epidemiology’. A clear developing trend was described, which began with fracture epidemiology and prevention, transitioned to perioperative management, orthogeriatric care and patient safety and then to functional recovery, disease burden and national audits in recent times. Conclusions Hip fractures result in conditions that extend far beyond orthopaedics concerning epidemiology and preventive medicine, internal medicine and endocrinology, as well as critical care and gerontology. Interest, research and publications are on the rise.

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Secular trends of hip fractures in France: impact of changing characteristics of the background population

Abstract: The incidence of hip fractures continues to grow despite a reduced incidence rate throughout a 12-year-period.

Cited by 21 publications

References 31 publications

Incidence and Time Trend of Hip Fractures in Romania: a Nationwide Study From 2008 to 2018

Incidence and Time Trend of Hip Fractures in Romania: a Nationwide Study From 2008 to 2018

High platelet-to-lymphocyte ratio predicts poor survival of elderly patients with hip fracture

Depicting developing trend and core knowledge of hip fracture research: a bibliometric and visualised analysis

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