In recent years, the use of mobile and cloud Computing is rapidly growing. In other word, mobile and cloud Computing play an important role in everybody's life today. It carries rich computational resources to mobile users, network operators, as well as cloud computing providers. Moreover, the explosion of multimedia big data (image, video, 3D, etc.) in mobile and cloud computing have created unprecedented opportunities and fundamental security and privacy challenges as they are not just big in volume, but also unstructured and multi-modal. Therefore, the papers of this special issue address variety of security and privacy issues of multimedia big data in mobile and cloud computing and security of other aspects of mobile and cloud networks and also emphasizes many open questions. We anticipate that papers of this special issue will open new entrance for further research and technology improvements in this important area.