In several industries, including healthcare, new technologies like blockchain and machine learning are being leveraged to generate innovative solutions. A blockchain network is used in the healthcare system, coupled with machine learning, to store and distribute patient data among hospitals, diagnostic labs, pharmaceutical companies, and clinicians. Applications based on Blockchain, and Machine Learning can precisely identify grave errors, including ones that could be fatal in the healthcare and medical industries. The efficiency, security, and transparency of sharing medical data can therefore be improved. Utilizing these two technologies allows medical institutions to gain knowledge and enhance patient data analysis. In this document, blockchain and Machine Learning were studied and their benefits to the process of the Healthcare Information Exchange Process. The benefits and characteristics of both the technologies and how they help with the process are discussed in a simple way. Blockchain works. Blockchain facilitates decentralized data protection in the healthcare industry and prevents specific risks while Decision-making, patient outcomes, and healthcare professional automation are all aided by Machine Learning in the interchange of healthcare information.